Product References
Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells.
Cell research
Liu C,Gong Y,Zhang H,Yang H,Zeng Y,Bian Z,Xin Q,Bai Z,Zhang M,He J,Yan J,Zhou J,Li Z,Ni Y,Wen A,Lan Y,Hu H,Liu B
Fri Oct 01 00:00:00 EDT 2021
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
Cell stem cell
Leimkühler NB,Gleitz HFE,Ronghui L,Snoeren IAM,Fuchs SNR,Nagai JS,Banjanin B,Lam KH,Vogl T,Kuppe C,Stalmann USA,Büsche G,Kreipe H,Gütgemann I,Krebs P,Banz Y,Boor P,Tai EW,Brümmendorf TH,Koschmieder S,Crysandt M,Bindels E,Kramann R,Costa IG,Schneider RK
Thu Apr 01 00:00:00 EDT 2021
Group-2 innate lymphoid cell-dependent regulation of tissue neutrophil migration by alternatively activated macrophage-secreted Ear11.
Mucosal immunology
Panova V,Gogoi M,Rodriguez-Rodriguez N,Sivasubramaniam M,Jolin HE,Heycock MWD,Walker JA,Rana BMJ,Drynan LF,Hodskinson M,Pannell R,King G,Wing M,Easton AJ,Oedekoven CA,Kent DG,Fallon PG,Barlow JL,McKenzie ANJ
Fri Jan 01 00:00:00 EST 2021
IL-3 is essential for ICOS-L stabilization on mast cells, and sustains the IL-33-induced RORγt+ Treg generation via enhanced IL-6 induction.
Immunology
Drube S,Müller S,Weber F,Wegner P,Böttcher-Loschinski R,Gaestel M,Hutloff A,Kamradt T,Andreas N
Sat May 01 00:00:00 EDT 2021
In Activated Murine Mast Cells, NFATc2 Is Critical for the Production of Autocrine IL-3, Thereby Promoting the Expression of IL-9.
Journal of immunology (Baltimore, Md. : 1950)
Sabbaghi F,Ullner L,Bohn T,Hahlbrock J,Bopp T,Schmitt E,Klein M,Stassen M
Fri Jan 01 00:00:00 EST 2021
Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.
Nature communications
Schumacher MA,Hsieh JJ,Liu CY,Appel KL,Waddell A,Almohazey D,Katada K,Bernard JK,Bucar EB,Gadeock S,Maselli KM,Washington MK,Grikscheit TC,Warburton D,Rosen MJ,Frey MR
210-33 was used in Sample Preparation to study whether Sprouty2 controls secretory cell differentiation and the response to colitis.
Fri Feb 05 00:00:00 EST 2021
Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.
Nature communications
Schumacher MA,Hsieh JJ,Liu CY,Appel KL,Waddell A,Almohazey D,Katada K,Bernard JK,Bucar EB,Gadeock S,Maselli KM,Washington MK,Grikscheit TC,Warburton D,Rosen MJ,Frey MR
210-33 was used in Sample Preparation to study whether Sprouty2 controls secretory cell differentiation and the response to colitis.
Fri Feb 05 00:00:00 EST 2021
Graft IL-33 regulates infiltrating macrophages to protect against chronic rejection.
The Journal of clinical investigation
Li T,Zhang Z,Bartolacci JG,Dwyer GK,Liu Q,Mathews LR,Velayutham M,Roessing AS,Lee YC,Dai H,Shiva S,Oberbarnscheidt MH,Dziki JL,Mullet SJ,Wendell SG,Wilkinson JD,Webber SA,Wood-Trageser M,Watkins SC,Demetris AJ,Hussey GS,Badylak SF,Turnquist HR
Thu Oct 01 00:00:00 EDT 2020
ILC2s are the predominant source of intestinal ILC-derived IL-10.
The Journal of experimental medicine
Bando JK,Gilfillan S,Di Luccia B,Fachi JL,Sécca C,Cella M,Colonna M
210-33 was used in Cell Culture to report the absence of an intestinal regulatory ILC population distinct from group 1 ILCs (ILC1s), ILC2s, and ILC3s in (1) mice bred in our animal facility; (2) mice from The Jackson Laboratory, Taconic Biosciences, and Charles River Laboratories; and (3) mice subjected to intestinal inflammation.
Mon Feb 03 00:00:00 EST 2020
COX Inhibition Increases Alternaria-Induced Pulmonary Group 2 Innate Lymphoid Cell Responses and IL-33 Release in Mice.
Journal of immunology (Baltimore, Md. : 1950)
Zhou W,Zhang J,Toki S,Goleniewska K,Norlander AE,Newcomb DC,Wu P,Boyd KL,Kita H,Peebles RS
Sat Aug 15 00:00:00 EDT 2020
CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response.
Cell reports
Bromley SK,Akbaba H,Mani V,Mora-Buch R,Chasse AY,Sama A,Luster AD
210-33 was used in In vitro experiments to study the requirement for CD49a in the formation, localization, persistence, and function of cutaneous CD8+ tissue-resident memory T cells.
Tue Sep 01 00:00:00 EDT 2020
Establishment of bone marrow-derived M-CSF receptor-dependent self-renewing macrophages.
Cell death discovery
Nasser H,Adhikary P,Abdel-Daim A,Noyori O,Panaampon J,Kariya R,Okada S,Ma W,Baba M,Takizawa H,Yamane M,Niwa H,Suzu S
Tue Sep 26 00:00:00 EDT 2023
The IL-33-induced p38-/JNK1/2-TNFα axis is antagonized by activation of β-adrenergic-receptors in dendritic cells.
Scientific reports
Helbig C,Weber F,Andreas N,Herdegen T,Gaestel M,Kamradt T,Drube S
Mon May 18 00:00:00 EDT 2020
IL-33-induced neutrophil extracellular traps degrade fibronectin in a murine model of bronchopulmonary dysplasia.
Cell death discovery
Jin R,Xu J,Gao Q,Mao X,Yin J,Lu K,Guo Y,Zhang M,Cheng R
Tue Sep 26 00:00:00 EDT 2023
A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.
Immunity
Minutti CM,Modak RV,Macdonald F,Li F,Smyth DJ,Dorward DA,Blair N,Husovsky C,Muir A,Giampazolias E,Dobie R,Maizels RM,Kendall TJ,Griggs DW,Kopf M,Henderson NC,Zaiss DM
Tue Mar 19 00:00:00 EDT 2019
Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation.
Proceedings of the National Academy of Sciences of the United States of America
Zhang C,Raveney BJE,Hohjoh H,Tomi C,Oki S,Yamamura T
Tue Oct 15 00:00:00 EDT 2019
IL-33 regulates cytokine production and neutrophil recruitment via the p38 MAPK-activated kinases MK2/3.
Immunology and cell biology
McCarthy PC,Phair IR,Greger C,Pardali K,McGuire VA,Clark AR,Gaestel M,Arthur JSC
Tue Jan 01 00:00:00 EST 2019
RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells.
Journal of immunology (Baltimore, Md. : 1950)
Andreas N,Potthast M,Geiselhöringer AL,Garg G,de Jong R,Riewaldt J,Russkamp D,Riemann M,Girard JP,Blank S,Kretschmer K,Schmidt-Weber C,Korn T,Weih F,Ohnmacht C
Fri Nov 15 00:00:00 EST 2019
Oncostatin M expression in the mouse uterus during early pregnancy promotes embryo implantation and decidualization.
FEBS letters
Fu T,Zheng HT,Zhang HY,Chen ZC,Li B,Yang ZM
210-33 was used in Cell Culture to study Osm high expression in the uterine epithelium from days 1 to 4 of pregnancy and in decidual cells on day 5 of pregnancy to indicate that prostaglandin E2 (PGE2 )-induced Osm may mediate embryo implantation through Il-33 and participate in decidualization via the Stat3-Egr1 pathway.
Thu Aug 01 00:00:00 EDT 2019
Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.
Nature communications
Miyamoto C,Kojo S,Yamashita M,Moro K,Lacaud G,Shiroguchi K,Taniuchi I,Ebihara T
Fri Jan 25 00:00:00 EST 2019
IL1RL1 is dynamically expressed on Cbfb-MYH11+ leukemia stem cells and promotes cell survival.
Scientific reports
Wang Y,Richter L,Becker M,Amador C,Hyde RK
Mon Feb 11 00:00:00 EST 2019
Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting.
Cell
Cohen M,Giladi A,Gorki AD,Solodkin DG,Zada M,Hladik A,Miklosi A,Salame TM,Halpern KB,David E,Itzkovitz S,Harkany T,Knapp S,Amit I
Thu Nov 01 00:00:00 EDT 2018
IL-33 promotes the egress of group 2 innate lymphoid cells from the bone marrow.
The Journal of experimental medicine
Stier MT,Zhang J,Goleniewska K,Cephus JY,Rusznak M,Wu L,Van Kaer L,Zhou B,Newcomb DC,Peebles RS
210-33 was used in Sample Preparation (FC/FACS) to study the critical role for IL-33 which is a hallmark peripheral ILC2-activating cytokine in the process of promoting the egress of ILC2 lineage cells from the bone marrow.
Tue Jan 02 00:00:00 EST 2018
IL-33 promotes the egress of group 2 innate lymphoid cells from the bone marrow.
The Journal of experimental medicine
Stier MT,Zhang J,Goleniewska K,Cephus JY,Rusznak M,Wu L,Van Kaer L,Zhou B,Newcomb DC,Peebles RS
210-33 was used in Sample Preparation (FC/FACS) to study the critical role for IL-33 which is a hallmark peripheral ILC2-activating cytokine in the process of promoting the egress of ILC2 lineage cells from the bone marrow.
Tue Jan 02 00:00:00 EST 2018
The PGI2 Analog Cicaprost Inhibits IL-33-Induced Th2 Responses, IL-2 Production, and CD25 Expression in Mouse CD4+ T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Zhou W,Zhang J,Toki S,Goleniewska K,Johnson MO,Bloodworth MH,Newcomb DC,Peebles RS
Mon Oct 01 00:00:00 EDT 2018
The p38-MK2/3 Module Is Critical for IL-33-Induced Signaling and Cytokine Production in Dendritic Cells.
Journal of immunology (Baltimore, Md. : 1950)
Göpfert C,Andreas N,Weber F,Häfner N,Yakovleva T,Gaestel M,Kamradt T,Drube S
Thu Feb 01 00:00:00 EST 2018
IL-4 enhances survival of in vitro-differentiated mouse basophils through transcription-independent signaling downstream of PI3K.
Cell death & disease
Reinhart R,Kaufmann T
Mon Jun 18 00:00:00 EDT 2018
Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice.
Communications biology
Willetts L,Felix LC,Jacobsen EA,Puttagunta L,Condjella RM,Zellner KR,Ochkur SI,Kim JD,Luo H,Lee NA,Lee JJ,Moqbel R,Lacy P
Sat Jan 11 00:00:00 EST 2020
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
Thu Sep 21 00:00:00 EDT 2017
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
Thu Sep 21 00:00:00 EDT 2017
Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion.
Immunity
Minutti CM,Drube S,Blair N,Schwartz C,McCrae JC,McKenzie AN,Kamradt T,Mokry M,Coffer PJ,Sibilia M,Sijts AJ,Fallon PG,Maizels RM,Zaiss DM
Tue Oct 17 00:00:00 EDT 2017
The Innate Cytokines IL-25, IL-33, and TSLP Cooperate in the Induction of Type 2 Innate Lymphoid Cell Expansion and Mucous Metaplasia in Rhinovirus-Infected Immature Mice.
Journal of immunology (Baltimore, Md. : 1950)
Han M,Rajput C,Hong JY,Lei J,Hinde JL,Wu Q,Bentley JK,Hershenson MB
Tue Aug 15 00:00:00 EDT 2017
Dectin-1 signaling inhibits osteoclastogenesis via IL-33-induced inhibition of NFATc1.
Oncotarget
Zhu X,Zhao Y,Jiang Y,Qin T,Chen J,Chu X,Yi Q,Gao S,Wang S
210-33 was used in Cell Culture to study the underlying mechanisms of how the agonist of dectin-1 inhibirs osteoclastogenesis and determine that curdlan potently inhibited RANKL-induced osteoclast differentiation and the resultant bone resorption.
Tue Aug 08 00:00:00 EDT 2017
IL-33 regulates the IgA-microbiota axis to restrain IL-1α-dependent colitis and tumorigenesis.
The Journal of clinical investigation
Malik A,Sharma D,Zhu Q,Karki R,Guy CS,Vogel P,Kanneganti TD
Thu Dec 01 00:00:00 EST 2016
Recent thymic emigrants are tolerized in the absence of inflammation.
The Journal of experimental medicine
Friesen TJ,Ji Q,Fink PJ
Mon May 30 00:00:00 EDT 2016
IL13 activates autophagy to regulate secretion in airway epithelial cells.
Autophagy
Dickinson JD,Alevy Y,Malvin NP,Patel KK,Gunsten SP,Holtzman MJ,Stappenbeck TS,Brody SL
210-33 was used in In vivo experiments to suggest that the regulation of autophagy by Th2 cytokines is cell-context dependent.
Tue Dec 13 00:00:00 EST 2016
IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha.
European journal of immunology
Jackson-Jones LH,Rückerl D,Svedberg F,Duncan S,Maizels RM,Sutherland TE,Jenkins SJ,McSorley HJ,Bénézech C,MacDonald AS,Allen JE
Sat Oct 01 00:00:00 EDT 2016
MK2/3 Are Pivotal for IL-33-Induced and Mast Cell-Dependent Leukocyte Recruitment and the Resulting Skin Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Drube S,Kraft F,Dudeck J,Müller AL,Weber F,Göpfert C,Meininger I,Beyer M,Irmler I,Häfner N,Schütz D,Stumm R,Yakovleva T,Gaestel M,Dudeck A,Kamradt T
Tue Nov 01 00:00:00 EDT 2016
Intratumorally Establishing Type 2 Innate Lymphoid Cells Blocks Tumor Growth.
Journal of immunology (Baltimore, Md. : 1950)
Kim J,Kim W,Moon UJ,Kim HJ,Choi HJ,Sin JI,Park NH,Cho HR,Kwon B
Tue Mar 01 00:00:00 EST 2016
MicroRNA-487b Is a Negative Regulator of Macrophage Activation by Targeting IL-33 Production.
Journal of immunology (Baltimore, Md. : 1950)
Xiang Y,Eyers F,Herbert C,Tay HL,Foster PS,Yang M
Fri Apr 15 00:00:00 EDT 2016
The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice.
Oncoimmunology
Mertz KD,Mager LF,Wasmer MH,Thiesler T,Koelzer VH,Ruzzante G,Joller S,Murdoch JR,Brümmendorf T,Genitsch V,Lugli A,Cathomas G,Moch H,Weber A,Zlobec I,Junt T,Krebs P
210-33 was used in Flow cytometry/Cell sorting to reveal a tumor-promoting role of IL-33/ST2 signaling in CRC.
Wed Mar 30 00:00:00 EDT 2022
The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development.
The Journal of experimental medicine
Yu Y,Wang C,Clare S,Wang J,Lee SC,Brandt C,Burke S,Lu L,He D,Jenkins NA,Copeland NG,Dougan G,Liu P
Mon Jun 01 00:00:00 EDT 2015
Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.
Journal of immunology (Baltimore, Md. : 1950)
Suzuki M,Morita R,Hirata Y,Shichita T,Yoshimura A
Sat Aug 01 00:00:00 EDT 2015
Composition, Development, and Function of Uterine Innate Lymphoid Cells.
Journal of immunology (Baltimore, Md. : 1950)
Doisne JM,Balmas E,Boulenouar S,Gaynor LM,Kieckbusch J,Gardner L,Hawkes DA,Barbara CF,Sharkey AM,Brady HJ,Brosens JJ,Moffett A,Colucci F
Thu Oct 15 00:00:00 EDT 2015
Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.
Nature communications
Cohen ES,Scott IC,Majithiya JB,Rapley L,Kemp BP,England E,Rees DG,Overed-Sayer CL,Woods J,Bond NJ,Veyssier CS,Embrey KJ,Sims DA,Snaith MR,Vousden KA,Strain MD,Chan DT,Carmen S,Huntington CE,Flavell L,Xu J,Popovic B,Brightling CE,Vaughan TJ,Butler R,Lowe DC,Higazi DR,Corkill DJ,May RD,Sleeman MA,Mustelin T
Mon Sep 14 00:00:00 EDT 2015
Regulation of Fc∈RI signaling in mast cells by G protein-coupled receptor kinase 2 and its RH domain.
The Journal of biological chemistry
Subramanian H,Gupta K,Parameswaran N,Ali H
Fri Jul 25 00:00:00 EDT 2014
Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Ohta S,Imamura M,Xing W,Boyce JA,Balestrieri B
Sat Jun 15 00:00:00 EDT 2013
IL-33 blockade suppresses the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.
Journal of neuroimmunology
Li M,Li Y,Liu X,Gao X,Wang Y
Fri Jun 15 00:00:00 EDT 2012
IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina.
Journal of immunology (Baltimore, Md. : 1950)
Nelson MP,Christmann BS,Werner JL,Metz AE,Trevor JL,Lowell CA,Steele C
Tue Feb 15 00:00:00 EST 2011
IL-33 exacerbates eosinophil-mediated airway inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Stolarski B,Kurowska-Stolarska M,Kewin P,Xu D,Liew FY
Wed Sep 15 00:00:00 EDT 2010
IL-33 reduces macrophage foam cell formation.
Journal of immunology (Baltimore, Md. : 1950)
McLaren JE,Michael DR,Salter RC,Ashlin TG,Calder CJ,Miller AM,Liew FY,Ramji DP
Thu Jul 15 00:00:00 EDT 2010
"Default" generation of neonatal regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Wang G,Miyahara Y,Guo Z,Khattar M,Stepkowski SM,Chen W
Thu Jul 01 00:00:00 EDT 2010
Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Ohno T,Oboki K,Kajiwara N,Morii E,Aozasa K,Flavell RA,Okumura K,Saito H,Nakae S
Tue Dec 15 00:00:00 EST 2009