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This peptide corresponds to 14 amino acids near the center of mouse KLRA3
PEP-0794 can be used as a blocking peptide with polyclonal antibody PA5-20676.
KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5E6; Killer cell lectin-like receptor 3; Ly-49c; Ly49I; Ly49I receptor; LY49I1; Lymphocyte antigen 49c; natural killer cell-associated antigen 2; Nk2.1; T-cell surface glycoprotein Ly-49C
Gene Aliases: 5E6; Klra3; Ly-49c; Ly49C; Nk-2; NK-2.1; Nk2; Nk2.1
UniProt ID: (Mouse) Q64329
Entrez Gene ID: (Mouse) 16634
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