Product References
Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
Blood
He H,Xu P,Zhang X,Liao M,Dong Q,Cong T,Tang B,Yang X,Ye M,Chang Y,Liu W,Wang X,Ju Z,Wang J
Thu Jul 09 00:00:00 EDT 2020
CCR5 deficiency impairs CD4+ T-cell memory responses and antigenic sensitivity through increased ceramide synthesis.
The EMBO journal
Martín-Leal A,Blanco R,Casas J,Sáez ME,Rodríguez-Bovolenta E,de Rojas I,Drechsler C,Real LM,Fabrias G,Ruíz A,Castro M,Schamel WW,Alarcón B,van Santen HM,Mañes S
Mon Aug 03 00:00:00 EDT 2020
Cytotoxic T cells swarm by homotypic chemokine signalling.
eLife
Galeano Niño JL,Pageon SV,Tay SS,Colakoglu F,Kempe D,Hywood J,Mazalo JK,Cremasco J,Govendir MA,Dagley LF,Hsu K,Rizzetto S,Zieba J,Rice G,Prior V,O'Neill GM,Williams RJ,Nisbet DR,Kramer B,Webb AI,Luciani F,Read MN,Biro M
Tue Oct 13 00:00:00 EDT 2020
CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis.
Cell death & disease
Lee D,Shin KJ,Kim DW,Yoon KA,Choi YJ,Lee BNR,Cho JY
Tue May 01 00:00:00 EDT 2018
CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis.
Cell death & disease
Lee D,Shin KJ,Kim DW,Yoon KA,Choi YJ,Lee BNR,Cho JY
Tue May 01 00:00:00 EDT 2018
Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance.
Nature communications
Meyer MA,Baer JM,Knolhoff BL,Nywening TM,Panni RZ,Su X,Weilbaecher KN,Hawkins WG,Ma C,Fields RC,Linehan DC,Challen GA,Faccio R,Aft RL,DeNardo DG
Wed Mar 28 00:00:00 EDT 2018
A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation.
The Journal of experimental medicine
McGarvey AC,Rybtsov S,Souilhol C,Tamagno S,Rice R,Hills D,Godwin D,Rice D,Tomlinson SR,Medvinsky A
Mon Dec 04 00:00:00 EST 2017
IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury.
Scientific reports
Thaney VE,O'Neill AM,Hoefer MM,Maung R,Sanchez AB,Kaul M
250-32 was used in In vitro experiments to illustrate the ability of exogenous IFNβ to mitigate HIVgp120-induced brain injury in rodents, acting as a neuroprotective agent.
Thu Apr 20 00:00:00 EDT 2017
IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury.
Scientific reports
Thaney VE,O'Neill AM,Hoefer MM,Maung R,Sanchez AB,Kaul M
250-32 was used in In vitro experiments to illustrate the ability of exogenous IFNβ to mitigate HIVgp120-induced brain injury in rodents, acting as a neuroprotective agent.
Thu Apr 20 00:00:00 EDT 2017
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Scientific reports
Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S
Tue Jun 27 00:00:00 EDT 2017
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
Scientific reports
Yagawa Y,Robertson-Tessi M,Zhou SL,Anderson ARA,Mulé JJ,Mailloux AW
Wed Nov 22 00:00:00 EST 2017
IL-5 triggers a cooperative cytokine network that promotes eosinophil precursor maturation.
Journal of immunology (Baltimore, Md. : 1950)
Fulkerson PC,Schollaert KL,Bouffi C,Rothenberg ME
Wed Oct 15 00:00:00 EDT 2014
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs.
The Journal of cell biology
Liou GY,Döppler H,Necela B,Krishna M,Crawford HC,Raimondo M,Storz P
Mon Aug 05 00:00:00 EDT 2013
IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection.
Journal of immunology (Baltimore, Md. : 1950)
Gwyer Findlay E,Villegas-Mendez A,de Souza JB,Inkson CA,Shaw TN,Saris CJ,Hunter CA,Riley EM,Couper KN
Wed May 01 00:00:00 EDT 2013
A combination of local inflammation and central memory T cells potentiates immunotherapy in the skin.
Journal of immunology (Baltimore, Md. : 1950)
Fiorenza S,Kenna TJ,Comerford I,McColl S,Steptoe RJ,Leggatt GR,Frazer IH
Sat Dec 15 00:00:00 EST 2012
Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.
Journal of immunology (Baltimore, Md. : 1950)
Schlecker E,Stojanovic A,Eisen C,Quack C,Falk CS,Umansky V,Cerwenka A
Sat Dec 15 00:00:00 EST 2012
IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro.
PloS one
Heller NM,Gwinn WM,Donnelly RP,Constant SL,Keegan AD
Fri Jan 04 00:00:00 EST 2013
An aberrant thymus in CCR5-/- mice is coupled with an enhanced adaptive immune response in fungal infection.
Journal of immunology (Baltimore, Md. : 1950)
Kroetz DN,Deepe GS
Sun May 15 00:00:00 EDT 2011
Pan-CC chemokine neutralization restricts splenocyte egress and reduces inflammation in a model of arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Buatois V,Fagète S,Magistrelli G,Chatel L,Fischer N,Kosco-Vilbois MH,Ferlin WG
Sun Aug 15 00:00:00 EDT 2010
Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family.
Lipids in health and disease
Kong W,Yen JH,Vassiliou E,Adhikary S,Toscano MG,Ganea D
Mon Feb 01 00:00:00 EST 2010
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Thu Feb 26 00:00:00 EST 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections.
Immunity
Kohlmeier JE,Miller SC,Smith J,Lu B,Gerard C,Cookenham T,Roberts AD,Woodland DL
Fri Jul 18 00:00:00 EDT 2008
Structure and function of A41, a vaccinia virus chemokine binding protein.
PLoS pathogens
Bahar MW,Kenyon JC,Putz MM,Abrescia NG,Pease JE,Wise EL,Stuart DI,Smith GL,Grimes JM
Tue Jan 01 00:00:00 EST 2008
CXCL10 blockade protects mice from cyclophosphamide-induced cystitis.
Journal of immune based therapies and vaccines
Sakthivel SK,Singh UP,Singh S,Taub DD,Novakovic KR,Lillard JW
Tue Oct 28 00:00:00 EDT 2008
HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection.
Cell death and differentiation
Kaul M,Ma Q,Medders KE,Desai MK,Lipton SA
Thu Feb 01 00:00:00 EST 2007
Galectin-3 regulates myofibroblast activation and hepatic fibrosis.
Proceedings of the National Academy of Sciences of the United States of America
Henderson NC,Mackinnon AC,Farnworth SL,Poirier F,Russo FP,Iredale JP,Haslett C,Simpson KJ,Sethi T
Tue Mar 28 00:00:00 EST 2006
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease.
Blood
Wysocki CA,Jiang Q,Panoskaltsis-Mortari A,Taylor PA,McKinnon KP,Su L,Blazar BR,Serody JS
Tue Nov 01 00:00:00 EST 2005
MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity.
Blood
Lillard JW,Singh UP,Boyaka PN,Singh S,Taub DD,McGhee JR
Sat Feb 01 00:00:00 EST 2003