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Mouse R-Spondin 1 Recombinant Protein, PeproTech®
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Product Details
315-32-1MG
Applications
Tested Dilution
Publications
Product Specifications
Species
Mouse
Published species
Mouse
Expression System
CHO cells
Amino acid sequence
SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCQEGLYL HKGRCYPACP EGSTAANSTM ECGSPAQCEM SEWSPWGPCS KKRKLCGFRK GSEERTRRVL HAPGGDHTTC SDTKETRKCT VRRTPCPEGQ KRRKGGQGRR ENANRHPARK NSKEPGSNSR RHKGQQQPQP GTTGPLTSVG PTWAQ
Molecular weight
27 kDa
Class
Recombinant
Type
Protein
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Amount
1 mg
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Murine R-Spondin-1 is a 27.1 kDa protein consisting of 245 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cristin-3; cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; mCristin-3; R-spondin homolog; roof plate-specific spondin-1; RP11-566C13.1; thrombospondin type 1 domain containing gene Rspondin; unnamed protein product
Gene Aliases: R-spondin; Rspondin
UniProt ID: (Mouse) Q9Z132
Entrez Gene ID: (Mouse) 192199
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