Annexin V Proteins

Protein Information

The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.

Synonyms

Anchorin CII; annexin 5; annexin A5; Annexin V; annexin-5; Anx5; ANXA5; Calphobindin I; CBP-I; Endonexin II; ENX2; epididymis secretory protein Li 7; HEL-S-7; LC5; lipocortin V; PAP-I; placental anticoagulant protein 4; Placental anticoagulant protein I; PP4; R74653; RPRGL3; Thromboplastin inhibitor; VAC-alpha; Vascular anticoagulant-alpha