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          PIK3CB/PIK3R2 Proteins

          PIK3CB/PIK3R2 Human recombinant proteins. Available Product Grades: Research Use Only. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us... PIK3CB/PIK3R2 Human recombinant proteins. Available Product Grades: Research Use Only. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... PIK3CB/PIK3R2 Human recombinant proteins. Available Product Grades: Research Use Only. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... PIK3CB/PIK3R2 Human recombinant proteins. Available Product Grades: Research Use Only. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

          Protein Information

          PIK3CB/PIK3R2 lipid kinase (p110 beta/p85 beta) or Phosphatidylinositol 3-kinase (PI3K) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids which functions in signaling pathways that regulate cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kDa catalytic subunit and a 85-kDa adaptor subunit. PIK3CB plays a critical role in regulating the formation and stability of alpha-2B-beta-3 integrin adhesion bonds, which are necessary for shear force-induced platelet activation. PIK3CB sustains alpha-2B-beta-3 integrin activation and stabilized platelet aggregation by regulating both integrin-dependent calcium flux and Gi activation of RAP1B.

          Synonyms

          PIK3CB; PIK3R2

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          Invitrogen
          Human PIK3CB/PIK3R2 (p110 beta/p85 beta), His Tag Recombinant Protein
          Invitrogen
          Human PIK3CB/PIK3R2 (p110 beta/p85 beta), His Tag Recombinant Protein
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          Cat # A31084

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