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          • Proteins & Peptides ›
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          TGFBR1 Proteins

          TGFBR1 Human recombinant proteins are validated for use in the following applications: Binding assay and Bioactivity. These proteins are expressed in Baculovirus and CHO cells. Available Product Grades: Research Use Only. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo... TGFBR1 Human recombinant proteins are validated for use in the following applications: Binding assay and Bioactivity. These proteins are expressed in Baculovirus and CHO cells. Available Product Grades: Research Use Only. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 2 proteins, including... TGFBR1 Human recombinant proteins are validated for use in the following applications: Binding assay and Bioactivity. These proteins are expressed in Baculovirus and CHO cells. Available Product Grades: Research Use Only. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 2 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... TGFBR1 Human recombinant proteins are validated for use in the following applications: Binding assay and Bioactivity. These proteins are expressed in Baculovirus and CHO cells. Available Product Grades: Research Use Only. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 2 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

          Protein Information

          TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1. TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).

          Synonyms

          AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Gibco
          Human TGFBR1 (soluble) Fc Recombinant Protein, PeproTech®
          Gibco
          Human TGFBR1 (soluble) Fc Recombinant Protein, PeproTech®
          Host
          Species
          Human
          Expression System
          CHO cells
          Product Grade
          Research Use Only
          Application
          Binding Bioactivity
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # 100-21R1-50UG
          Invitrogen
          Human TGFBR1 (ALK5), GST Tag Recombinant Protein
          Invitrogen
          Human TGFBR1 (ALK5), GST Tag Recombinant Protein
          Host
          Species
          Human
          Expression System
          Baculovirus
          Product Grade
          Research Use Only
          Application
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # PV5837

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