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Understanding brain and neuro-functions
Studying the brain and neuro-functions requires the knowledge of a vast selection of experimental methods, from cell preparation to image acquisition and analysis. Thermo Scientific Amira Software supports you in the most frequently used image analysis techniques, such as filament tracing and editing, DTI analysis, brain perfusion analysis, and object tracking. Combining Amira Software's versatility with state-of-the-art 3D visualization and image processing enables you to create custom workflows that extract exactly the desired type of information from an image.
Imaging data
Processing
Visualization
Analysis
Insight from your peers
Explore industry-leading insights and research that can support your lab workflow. Amira Software can empower your lab with a cutting-edge, comprehensive imaging data analysis toolbox.
Helping scientists answer questions that enable breakthrough discoveries in life sciences, materials science, and industry.
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Understanding the complexity of cancer with correlative light electron microscopy and Amira Software
Understanding the interconnectivity of the brain is essential for functional brain research. This allows researchers to better understand how different parts of the brain jointly orchestrate higher cognitive functions and motor skills.
With Amira Software, you are able to perform the entire DTI analysis workflow by first converting images into Talairach coordinates. You are then able to map multiple brain images onto a reference brain. Once the brain images are aligned, gradient images can be converted into a tensor field, and nerve fiber bundles can be tracked and visualized with our state-of-the-art visualization tools.
With Amira Software, you are able to trace, analyze, and quantify 3D images of filamentous structures such as neurons and blood vessels. Filamentous networks can be reconstructed, and measures such as length, thickness, orientation, ranks, etc., can be computed and visualized in compelling 3D renderings. Tracing can be performed automatically or interactively, depending on the application and needs.
Our template-matching algorithm allows automatic detection and tracing of fine filaments in noisy cryo-EM data. Amira Software also enables you to edit the resulting graphs to remove image features erroneously identified as a filament or to add missing parts of a network.
Brain perfusion studies help researchers and scientist to understand the impact of strokes or other brain tissue diseases such as Alzheimer and dementia. The exact location and duration of a stroke can determine functional impact of the event.
With Amira Software, you are able to analyze brain perfusion in perfusion-weighted MRI and CT images. This analysis includes computation of mean transit time (MTT), cerebral blood flow (CBF), and cerebral blood volume (CBV).
In vitro neuroscience research has grown considerably in neurodegenerative, neurogenesis, and neurotoxicology applications. Neurite outgrowth and synaptogenesis are the gold standards for evaluating health and functionality of neurons. However, even in vitro, identification of neuronal outgrowth morphology is difficult.
Researchers manually tracing neurites and synaptogenic spots face variability and non-scalability. Amira Software’s three-dimensional neuroscience abilities can accurately and efficiently quantify neuronal morphology in 3D models to facilitate the high-throughput demands of this research.
Understanding the interconnectivity of the brain is essential for functional brain research. This allows researchers to better understand how different parts of the brain jointly orchestrate higher cognitive functions and motor skills.
With Amira Software, you are able to perform the entire DTI analysis workflow by first converting images into Talairach coordinates. You are then able to map multiple brain images onto a reference brain. Once the brain images are aligned, gradient images can be converted into a tensor field, and nerve fiber bundles can be tracked and visualized with our state-of-the-art visualization tools.
With Amira Software, you are able to trace, analyze, and quantify 3D images of filamentous structures such as neurons and blood vessels. Filamentous networks can be reconstructed, and measures such as length, thickness, orientation, ranks, etc., can be computed and visualized in compelling 3D renderings. Tracing can be performed automatically or interactively, depending on the application and needs.
Our template-matching algorithm allows automatic detection and tracing of fine filaments in noisy cryo-EM data. Amira Software also enables you to edit the resulting graphs to remove image features erroneously identified as a filament or to add missing parts of a network.
Brain perfusion studies help researchers and scientist to understand the impact of strokes or other brain tissue diseases such as Alzheimer and dementia. The exact location and duration of a stroke can determine functional impact of the event.
With Amira Software, you are able to analyze brain perfusion in perfusion-weighted MRI and CT images. This analysis includes computation of mean transit time (MTT), cerebral blood flow (CBF), and cerebral blood volume (CBV).
In vitro neuroscience research has grown considerably in neurodegenerative, neurogenesis, and neurotoxicology applications. Neurite outgrowth and synaptogenesis are the gold standards for evaluating health and functionality of neurons. However, even in vitro, identification of neuronal outgrowth morphology is difficult.
Researchers manually tracing neurites and synaptogenic spots face variability and non-scalability. Amira Software’s three-dimensional neuroscience abilities can accurately and efficiently quantify neuronal morphology in 3D models to facilitate the high-throughput demands of this research.
입문 교육
Amira, Avizo 및 PerGeos Software 신규 사용자를 위해 특별히 설계된 이 입문 교육을 통해 학습 커브를 단축하고 투자를 극대화 해보세요.
이 교육은 실습 교육이 있는 강의로 이루어져 있습니다. 교육 자료는 Amira, Avizo 및 PerGeos Software의 기본 기능과 특징을 조명합니다.
고급 교육
Amira, Avizo 및 PerGeos Software의 기존 사용자를 위해 특별히 설계된 이 고급 교육을 통해 결과를 얻기 까지의 시간을 단축하고 투자를 극대화 해보세요.
이 교육은 실습 교육이 있는 강의로 이루어져 있습니다. 교육 자료는 Amira, Avizo 및 PerGeos Software의 고급 기능과 특징을 조명합니다.
맞춤형 개발
3D 및 이미지 프로세싱에서의 25년 이상의 경험과 크고 작은 조직에 수 백개의 맞춤형 프로젝트를 제공해 온 Thermo Fisher Scientific은 특정 요구에 맞는 맞춤형 솔루션을 제공할 수 있습니다.
저희는 당사의 소프트웨어를 다양한 수준으로 맞춤화하고 확장할 수 있습니다.
Visualization of the results of a Diffusion Tensor Imaging study of the human head Courtesy of Prof. Dr. Alexander Brawanski, University Hospital of Regensburg1001.
Visualization of a brain of Mus musculus.
Fertilizers effects on neuronal outgrowth and synapse expression by IUF – Leibniz Research Institute for Environmental Medicine.
Analysis of the neurites of a neurospheroid. Data courtesy of Dr. Stefan Masjosthusmann, IUF – Leibniz Research Institute for Environmental Medicine.
Visualization of the results of a Diffusion Tensor Imaging study of the human head. Courtesy of Prof. Dr. Alexander Brawanski, University Hospital of Regensburg.
Volume rendering of cleared spinal cord as imaged with 2-photon microscopy. Data courtesy of Ali Ertürk, Max Planck Institute of Neurobiology.
Tube rendering of traced axons colorized according to axon thickness. Data courtesy of Ali Ertürk, Max Planck Institute of Neurobiology.
Paired Helical Filaments (PHF). Data courtesy of The Medical Research Council Laboratory of Molecular Biology. Fitzpatrick et al., 2017.Data courtesy of The Medical Research Council Laboratory of Molecular Biology. Fitzpatrick et al., 2017.
Visualization of the results of a Diffusion Tensor Imaging study of the human head Courtesy of Prof. Dr. Alexander Brawanski, University Hospital of Regensburg1001.
Visualization of a brain of Mus musculus.
Fertilizers effects on neuronal outgrowth and synapse expression by IUF – Leibniz Research Institute for Environmental Medicine.
Analysis of the neurites of a neurospheroid. Data courtesy of Dr. Stefan Masjosthusmann, IUF – Leibniz Research Institute for Environmental Medicine.
Visualization of the results of a Diffusion Tensor Imaging study of the human head. Courtesy of Prof. Dr. Alexander Brawanski, University Hospital of Regensburg.
Volume rendering of cleared spinal cord as imaged with 2-photon microscopy. Data courtesy of Ali Ertürk, Max Planck Institute of Neurobiology.
Tube rendering of traced axons colorized according to axon thickness. Data courtesy of Ali Ertürk, Max Planck Institute of Neurobiology.
Paired Helical Filaments (PHF). Data courtesy of The Medical Research Council Laboratory of Molecular Biology. Fitzpatrick et al., 2017.Data courtesy of The Medical Research Council Laboratory of Molecular Biology. Fitzpatrick et al., 2017.
이미징 데이터 가져오기 및 프로세스
- 모든 종류, 스케일, 사이즈 처리:
- Bio-Formats
- Bitmap 형식
- 현미경: 전자 및 광학
- 의학 및 뉴로이미지 형식
- 분자 형식
- 기타 획득 장치 (MRI, 방사선 촬영 등)
- 유한 요소 모델링, 기하학적 모델링, CAD
- 다중 데이터/다중 뷰, 다중 채널, 타임 시리즈, 대량 데이터 지원
- 스케일링, 보정, 변환, 리샘플링(re-sampling)
- 이미지 개선, 종합적인 필터링 및 컨볼루션, 푸리에 주파수 변환
- 아티팩트(artifact) 감소 알고리즘
- 고급 다중 모드 2D/3D 자동 등록
- 이미지 스택 정렬, 산술, 상관 관계, 결합
이미징 데이터를 쉽게 세분화
- 임계값 계산 및 자동 세분화, 개체 분리, 자동 레이블 지정
- 영역 확대, 스네이크, 보간, 래핑, 평활
- 유역 및 분지를 포함한 형태학적 처리
- 머신 러닝 기반 세분화
- 개별 섬유 및 필라멘트 자동 추적
- 골격화 및 필라멘트 네트워크 추출
- 분할 및 공간 그래프 생성이나 편집을 위한 상호작용식 도구
- 3D 표면 재현
- FEA/CFD를 위한 그리드 생성
분석 및 시각화 작업을 원활하게 출판하고 발표하기 위해 내보내기(export) 하세요.
- 애니메이션 및 동영상 생성
- 고급 키 프레임 및 객체 애니메이션
- 이미지, 기하학적 모델, 측정 및 시뮬레이션 혼합
- 주석, 측정 범례, 히스토그램 및 곡선 플롯
- 스프레드시트 내보내기, 3D 모델, 고품질 이미지
- 능동 및 수동 방식 3D 스테레오 비전
- 단일 및 타일형 화면 디스플레이
- 몰입형 환경
이미징 데이터를 시각화하고 탐색해보세요.
- 상호작용식 고품질 볼륨 및 멀티채널 시각화
- 직교, 경사, 원통형 및 곡선 슬라이싱
- 윤곽 및 등면(iso-surface) 추출
- 최대 강도 또는 기타 유형의 투영
- 벡터 및 텐서 시각화
- 객체 및 추적
- 분자적 시각화
이미징 데이터를 분석하고 정량적 정보를 얻어보세요.
- 직관적인 레시피 생성, 사용자 맞춤화, 자동 재생
- 카운트, 볼륨, 영역, 경계선, 가로세로비 및 방향을 포함한 측정 방법 내장
- 사용자 정의 측정
- 스프레드시트 도구 및 차트를 사용하는 결과 뷰어
- 자동 개별 형상 측정, 3D 국소화 및 스프레드시트 선택
- 통계 자동화, 분포 그래프
- 측정 기준을 사용한 형상 필터링
- 데이터 정합, 변형, 비교 및 측정
Amira Software를 특별한 요구에 맞게 쉽고 신속하게 조정해보세요.
- 맞춤형 C++ 모듈 개발
- MATLAB™ bridge
- Python 스크립팅 API
For Research Use Only. Not for use in diagnostic procedures.
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