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          • Home
          • › Search Tool
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          • › Hs01084494_m1
          See other LEP GE Assays ›
          Gene Symbol:
          LEP
          Gene Name:
          leptin
          Gene Aliases:
          LEPD, OB, OBS
          Chromosome Location:
          Chr.7: 128241201 - 128257629 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs01084494_m1
          Size
          Availability Made To Order
          Catalog # 4351372
          Price 435.00
          Your Price
          Online offer: 408.65
          408.65
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: LEP
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_000230.2 NP_000221.1 1 - 2 31 70
          XM_005250340.4 XP_005250397.1 1 - 2 108 70
          GenBank mRNA AK313553.1 - 1 - 2 29 70
          BC060830.1 - 1 - 2 30333193 70
          DA762132.1 - 1 - 2 31 70
          U43653.1 - 69

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          More Information


          Updated Mapping Information

          This assay targets the same location as Clariom D transcript cluster(s) TC0700009036.hg.1
          This assay targets the same location as HTA transcript cluster(s) TC07000768.hg.1

          Additional Information:

          This assay is in the 5'UTR region of the AK313553.1,BC060830.1,NM_000230.2,U43653.1,XM_005250340.4 transcripts.

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 3' Most Mammalian Gene Collection Homo sapiens Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene LEP

          Panther Classification:

          Molecular Function -

          peptide hormone

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          angiogenesis
          ovulation from ovarian follicle
          response to hypoxia
          positive regulation of cytokine production
          placenta development
          regulation of endothelial cell proliferation
          response to dietary excess
          cardiac muscle hypertrophy
          glucose metabolic process
          regulation of gluconeogenesis
          energy reserve metabolic process
          glycerol biosynthetic process
          lipid metabolic process
          fatty acid beta-oxidation
          tyrosine phosphorylation of STAT protein
          female pregnancy
          circadian rhythm
          cholesterol metabolic process
          bile acid metabolic process
          regulation of blood pressure
          adult feeding behavior
          negative regulation of autophagy
          negative regulation of lipid storage
          positive regulation of phosphatidylinositol 3-kinase signaling
          response to activity
          sexual reproduction
          central nervous system neuron development
          insulin secretion
          T cell differentiation
          regulation of intestinal cholesterol absorption
          positive regulation of TOR signaling
          negative regulation of appetite
          prostaglandin secretion
          response to estradiol
          regulation of natural killer cell activation
          regulation of natural killer cell proliferation
          response to insulin
          response to vitamin E
          leptin-mediated signaling pathway
          positive regulation of luteinizing hormone secretion
          positive regulation of peroxisome proliferator activated receptor signaling pathway
          bone mineralization involved in bone maturation
          negative regulation of appetite by leptin-mediated signaling pathway
          positive regulation of T cell proliferation
          regulation of natural killer cell mediated cytotoxicity
          hormone metabolic process
          positive regulation of tyrosine phosphorylation of Stat3 protein
          glucose homeostasis
          eating behavior
          negative regulation of apoptotic process
          positive regulation of ion transport
          positive regulation of MAPK cascade
          cellular response to leptin stimulus
          response to ethanol
          positive regulation of myeloid cell differentiation
          regulation of angiogenesis
          negative regulation of vasoconstriction
          negative regulation of glucose import
          positive regulation of JAK-STAT cascade
          positive regulation of insulin receptor signaling pathway
          regulation of bone remodeling
          positive regulation of follicle-stimulating hormone secretion
          positive regulation of developmental growth
          regulation of insulin secretion
          regulation of steroid biosynthetic process
          intestinal absorption
          leukocyte tethering or rolling
          regulation of nitric-oxide synthase activity
          regulation of cell cycle
          positive regulation of protein kinase B signaling
          regulation of lipoprotein lipid oxidation
          adipose tissue development
          negative regulation of cartilage development
          negative regulation of glucagon secretion
          cellular response to L-ascorbic acid
          cellular response to retinoic acid
          interleukin-6 secretion
          interleukin-8 secretion
          regulation of brown fat cell differentiation
          bone growth
          regulation of cytokine production involved in inflammatory response
          positive regulation of p38MAPK cascade
          positive regulation of fat cell apoptotic process
          activation of protein kinase C activity
          positive regulation of STAT protein import into nucleus
          positive regulation of reactive oxygen species metabolic process
          negative regulation of glutamine transport
          positive regulation of hepatic stellate cell activation
          hormone activity
          growth factor activity
          peptide hormone receptor binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR07012167.hg.1 NM_000230.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR07012167.hg.1 TC07000768.hg.1 HTA TC
          Affymetrix Human Transcriptome Array 2.0 PSR07012169.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR07012169.hg.1 NM_000230.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR07012169.hg.1 TC07000768.hg.1 HTA TC
          Affymetrix Human Transcriptome Array 2.0 PSR07012168.hg.1 NM_000230.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR07012168.hg.1 TC07000768.hg.1 HTA TC
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay TC0700009036.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay PSR0700164063.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay PSR0700164063.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay PSR0700164063.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay PSR0700164063.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay PSR0700164063.hg.1 TC0700009036.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR0700164062.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay PSR0700164062.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay PSR0700164062.hg.1 ENST00000308868.4 Ensembl
          Affymetrix Human Clariom D Assay PSR0700164062.hg.1 NM_000230.2 Refseq
          Affymetrix Human Clariom D Assay PSR0700164062.hg.1 TC0700009036.hg.1 Clariom D TC

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