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          • › Mm00468600_g1
          See other HES1 GE Assays ›
          Gene Symbol:
          Hes1
          Gene Name:
          hairy and enhancer of split 1 (Drosophila)
          Gene Aliases:
          Hry, bHLHb39
          Chromosome Location:
          Chr.16: 30065357 - 30067796 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00468600_g1
          Size
          Availability Made To Order
          Catalog # 4351372
          Price 435.00
          Your Price
          Online offer: 408.65
          408.65
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: Hes1
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_008235.2 NP_032261.1 1 - 2 346 63
          GenBank mRNA AK132536.1 - 1 - 2 357 63
          AK133538.1 - 1 - 2 362 63
          BC018375.1 - 1 - 2 346 4505427 63
          BC051428.1 - 1 - 2 347 6478994 63

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC1600000392.mm.1

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Mammalian Gene Collection Detect Genomic DNA Mus musculus Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Hes1

          Panther Classification:

          Molecular Function -

          basic helix-loop-helix transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          in utero embryonic development
          liver development
          embryonic heart tube morphogenesis
          outflow tract morphogenesis
          regulation of secondary heart field cardioblast proliferation
          ventricular septum development
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          protein complex assembly
          cell adhesion
          Notch signaling pathway
          smoothened signaling pathway
          STAT protein import into nucleus
          pattern specification process
          positive regulation of cell proliferation
          positive regulation of gene expression
          negative regulation of gene expression
          negative regulation of neuron projection development
          cell migration
          telencephalon development
          midbrain-hindbrain boundary morphogenesis
          oculomotor nerve development
          trochlear nerve development
          hindbrain morphogenesis
          forebrain radial glial cell differentiation
          neural tube development
          pituitary gland development
          adenohypophysis development
          lung development
          positive regulation of BMP signaling pathway
          midbrain development
          pancreas development
          somatic stem cell population maintenance
          hair cell differentiation
          aorta morphogenesis
          ascending aorta morphogenesis
          positive regulation of T cell proliferation
          auditory receptor cell differentiation
          positive regulation of tyrosine phosphorylation of Stat3 protein
          auditory receptor cell fate determination
          positive regulation of DNA binding
          regulation of protein heterodimerization activity
          cell fate commitment
          negative regulation of cell differentiation
          regulation of fat cell differentiation
          negative regulation of auditory receptor cell differentiation
          negative regulation of neuron differentiation
          positive regulation of glial cell differentiation
          positive regulation of Notch signaling pathway
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of mitotic cell cycle, embryonic
          lateral inhibition
          positive regulation of JAK-STAT cascade
          cell maturation
          regulation of timing of cell differentiation
          thymus development
          cell morphogenesis involved in neuron differentiation
          positive regulation of astrocyte differentiation
          negative regulation of oligodendrocyte differentiation
          artery morphogenesis
          regulation of neurogenesis
          negative regulation of neurogenesis
          regulation of timing of neuron differentiation
          negative regulation of glial cell proliferation
          ventricular septum morphogenesis
          labyrinthine layer blood vessel development
          common bile duct development
          negative regulation of stomach neuroendocrine cell differentiation
          cardiac neural crest cell development involved in outflow tract morphogenesis
          pharyngeal arch artery morphogenesis
          cochlea development
          negative regulation of calcium ion import
          vascular smooth muscle cell development
          neuronal stem cell population maintenance
          negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
          positive regulation of protein targeting to mitochondrion
          cellular response to nerve growth factor stimulus
          negative regulation of pancreatic A cell differentiation
          negative regulation of stem cell differentiation
          negative regulation of pro-B cell differentiation
          negative regulation of forebrain neuron differentiation
          negative regulation of inner ear receptor cell differentiation
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
          DNA binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          transcription factor binding
          JUN kinase binding
          protein complex binding
          protein homodimerization activity
          histone deacetylase binding
          sequence-specific DNA binding
          protein dimerization activity
          chaperone binding
          E-box binding
          N-box binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR1600003732.mm.1 NM_008235.2.1 Refseq
          Affymetrix Mouse Clariom S Array PSR1600003732.mm.1 NM_008235.2 Refseq
          Affymetrix Mouse Clariom S Array PSR1600003732.mm.1 TC1600000392.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR1600003734.mm.1 NM_008235.2.1 Refseq
          Affymetrix Mouse Clariom S Array PSR1600003734.mm.1 NM_008235.2 Refseq
          Affymetrix Mouse Clariom S Array PSR1600003734.mm.1 TC1600000392.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR1600003733.mm.1 NM_008235.2.1 Refseq
          Affymetrix Mouse Clariom S Array PSR1600003733.mm.1 NM_008235.2 Refseq
          Affymetrix Mouse Clariom S Array PSR1600003733.mm.1 TC1600000392.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR1600003735.mm.1 NM_008235.2.1 Refseq
          Affymetrix Mouse Clariom S Array PSR1600003735.mm.1 NM_008235.2 Refseq
          Affymetrix Mouse Clariom S Array PSR1600003735.mm.1 TC1600000392.mm.1 MTA TC

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