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          • Home
          • › Search Tool
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          • › Mm01304122_m1
          See other LRRK2 GE Assays ›
          Gene Symbol:
          Lrrk2
          Gene Name:
          leucine-rich repeat kinase 2
          Gene Aliases:
          4921513O20Rik, 9330188B09Rik, AW561911, D630001M17Rik, Gm927, cI-46
          Chromosome Location:
          Chr.15: 91672821 - 91816124 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm01304122_m1
          Size
          Availability Made To Order
          Catalog # 4351372
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: Lrrk2
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_025730.3 NP_080006.3 19 - 20 2553 95
          GenBank mRNA AK052591.1 - 19 - 20 2554 95
          AY792512.1 - 19 - 20 2496 95

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC1500000897.mm.1

          Set Membership:

          Ambion siRNA available Amplicon length between 86 and 100 Mus musculus Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Lrrk2

          Panther Classification:

          Molecular Function -

          scaffold/adaptor protein

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          activation of MAPKK activity
          activation of MAPK activity
          negative regulation of protein phosphorylation
          positive regulation of protein phosphorylation
          protein phosphorylation
          endocytosis
          autophagy
          response to oxidative stress
          mitochondrion organization
          Golgi organization
          small GTPase mediated signal transduction
          neuromuscular junction development
          determination of adult lifespan
          positive regulation of autophagy
          regulation of protein kinase A signaling
          negative regulation of protein processing
          regulation of neuron maturation
          phosphorylation
          peptidyl-serine phosphorylation
          peptidyl-threonine phosphorylation
          olfactory bulb development
          tangential migration from the subventricular zone to the olfactory bulb
          cell differentiation
          positive regulation of protein ubiquitination
          negative regulation of protein binding
          positive regulation of protein binding
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          negative regulation of GTPase activity
          cellular response to oxidative stress
          cellular protein localization
          intracellular signal transduction
          regulation of kidney size
          exploration behavior
          locomotory exploration behavior
          synaptic vesicle recycling
          regulation of locomotion
          regulation of membrane potential
          positive regulation of programmed cell death
          positive regulation of GTPase activity
          GTP metabolic process
          protein autophosphorylation
          intracellular distribution of mitochondria
          neuron projection morphogenesis
          mitochondrion localization
          regulation of mitochondrial depolarization
          regulation of synaptic transmission, glutamatergic
          excitatory postsynaptic potential
          regulation of dopamine receptor signaling pathway
          positive regulation of dopamine receptor signaling pathway
          regulation of dendritic spine morphogenesis
          neuron death
          cellular response to manganese ion
          reactive oxygen species metabolic process
          regulation of neuron death
          negative regulation of neuron death
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          positive regulation of protein autoubiquitination
          regulation of neuroblast proliferation
          regulation of synaptic vesicle transport
          negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation
          negative regulation of hydrogen peroxide-induced cell death
          negative regulation of protein targeting to mitochondrion
          cellular response to dopamine
          regulation of branching morphogenesis of a nerve
          regulation of synaptic vesicle exocytosis
          negative regulation of peroxidase activity
          SNARE binding
          nucleotide binding
          glycoprotein binding
          actin binding
          GTPase activity
          protein kinase activity
          protein serine/threonine kinase activity
          MAP kinase kinase activity
          GTPase activator activity
          protein binding
          ATP binding
          GTP binding
          tubulin binding
          kinase activity
          transferase activity
          transferase activity, transferring phosphorus-containing groups
          Rho GTPase binding
          syntaxin-1 binding
          clathrin binding
          GTP-dependent protein kinase activity
          peroxidase inhibitor activity
          identical protein binding
          protein homodimerization activity
          ion channel binding
          protein kinase A binding

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