Custom siRNA and miRNA products provide a tailored solution for researchers looking to implement RNA interference in their studies. We offer high-quality synthesis and flexible customization options to help ensure researchers achieve precise and efficient gene silencing results.

Custom siRNA and miRNA design and ordering tools

By using our design tools, you can create custom sequences for any organism. The designers can create custom duplexes based on a cDNA sequence, Entrez ID or GenBank accession number, or by entering your existing sequence.

Custom designed siRNA duplexes provide

  • Designs using our proprietary Silencer Select algorithm for creating highly potent and specific designs
  • All of the advantages of the chosen product chemistry
  • Matched controls for any organism
Products supportedCustomization needOrdering tool
Silencer Select siRNA
Silencer siRNA
Ambion In Vivo siRNA
  • Transcript specific targeted siRNA
  • siRNA for species other than human, mouse, and rat
  • Custom siRNA sequences
GeneAssist siRNA
mirVana miRNA inhibitors
mirVana miRNA mimics
Ambion Anti-miR miRNA Inhibitors
Ambion Pre-miR miRNA Precursors
  • Custom miRNA sequences not available in our predesigned catalog
GeneAssist miRNA
Stealth RNAi siRNA
shRNA
  • Custom Stealth RNAi siRNA sequence
  • Convert an existing siRNA sequence to Stealth RNAi siRNA
  • Designing shRNA sequences for specific genes
  • Converting siRNA to shRNA
RNAi Designer
Single-stranded RNA
  • Synthesis of up to 50 nucleotides
Custom RNA Oligos

High quality siRNA synthesis

We synthesize and purify each siRNA in state-of-the-art facilities to meet the highest quality standards. As part of our rigorous quality control procedures, each RNA oligonucleotide is analyzed by MALDI-TOF mass spectrometry and/or analytical HPLC. To offer the utmost in quality, we also assess each annealed siRNA by gel electrophoresis to confirm that the strands annealed properly. The result is premium quality siRNA that is purified and ready to use.

Custom siRNA and miRNA libraries

For those requiring custom libraries, we provide plated sets of siRNAs and miRNA mimics and inhibitors designed to target your list of genes.

See our flyer for available library information
Contact us today for a quote

Resources
Questions?

Technical inquires:
Our Technical Application Scientists are available to help assist you at techsupport@thermofisher.com

Ordering & Order Status inquires:
If you have questions about pre-designed RNAi orders and order status, please contact us at genomicorders@thermofisher.com

If you have any questions about Custom RNAi orders and order status, please contact us at RNAiSupport@thermofisher.com

For Research Use Only. Not for use in diagnostic procedures.

Hero banner dark gradient overlay
Stylesheet for Classic Wide Template adjustments