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Mass Spectrometry Support Center
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Liquid Chromatography Mass Spectrometry Instruments Support
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Q Exactive Plus Hybrid Quadrupole Orbitrap Mass Spectrometer Support
Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer Support
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Liquid Chromatography Mass Spectrometry Instruments Support
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Exactive Plus Orbitrap Mass Spectrometer Support
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Exactive Plus EMR Orbitrap Mass Spectrometer Support
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Q Exactive HF-X Hybrid Quadrupole Orbitrap Mass Spectrometer Support
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Q Exactive Plus Hybrid Quadrupole Orbitrap Mass Spectrometer Support
Q Exactive Plus Hybrid Quadrupole Orbitrap Mass Spectrometer Support - Getting Started
Q Exactive Plus Hybrid Quadrupole Orbitrap Mass Spectrometer Support - Troubleshooting
Q Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer Support
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Explore our “Getting Started” and “Troubleshooting” sections for solutions to top inquiries and common problems. Browse through our "Guides and Tools" section to access a comprehensive portfolio of product-related support resources.
Getting Started
What does a mass deviation of 3 ppm mean?
What is the most sensitive measurement mode?
How do I find the optimal settings for Automated Gain Control (AGC) and maximum injection time (IT)?
Which resolution settings do I choose for different scan modes for the quantification of small molecules?
How often do I have to calibrate?
Can I do polarity switching? What is the time for polarity switching?
What is AGC?
What is High Energy Collision Dissociation (HCD)?
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Troubleshooting
Why does the metal needle insert in the heated ESI probe frequently clog?
Why does the tune software show bad vacuum?
Why is the temperature of UHV chamber higher than expected?
The turbomolecular pump is not operating.
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Guides and Tools
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Search our database for Product Documents:
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Brochure: Q Exactive Plus Orbitrap LC-MS/MS System
Application Notes
Application Note: TMT Workflow on the Q Exactive Series - Instrument Parameter Optimization and Data Analysis in Proteome Discoverer 2.1 Software
Application Note: Subunit Analysis Approach for the Determination of Fucosylation Levels in Monoclonal Antibodies Using LC-HRAM-MS
Application Note: IdeS-Cleaved mAb Subunit Analysis with LC-HRAM-MS: A Quick and Accurate Comparison of Biosimilar and Originator Biotherapeutics
Posters and Presentations
Poster Note: Characterization of Monoclonal Antibodies and ADCs using a Benchtop Orbitrap Mass Spectrometer
Poster Note: Characterization of Monoclonal Antibodies Oxidation Variants Using Middle-down Approach and Hydrogen/Deuterium Exchange Mass Spectrometry
Poster Note: Fast Analysis of Therapeutic Monoclonal Antibodies, Fragments, and Oxidation Variants Using a Super-Macro Porous Reversed-Phase Column Coupled with an Orbitrap Mass Spectrometer
Poster Note: The Oxidized Proteome of Peripheral Blood Mononuclear Cells: A Valuable Repository for Clinical Proteomics
Technical Notes
Technical Note: Quantification of 25-hydroxyvitamin D2 and D3 in human plasma by liquid chromatography coupled to high-resolution Orbitrap mass spectrometry for clinical research
Technical Note: Quantification of tricyclic antidepressants in human plasma or serum by LC-HRAM(MS) for clinical research
Technical Note: Quantification of antiepileptics in human plasma or serum by LC-HRAM(MS) for clinical research
Training, Events, and Webinars
Classroom Training: Exactive Family
HPLC Tips and Tricks Webinars
Tools, Software, and Calculators
Thermo Fisher Cloud:
a secure place to store, analyze, and share data
AppsLab Library:
Fully searchable repository of LC, IC, GC, GC-MS and LC-MS methods
XCalibur Software:
Control, and process data from, Thermo Scientific LC-MS systems
TraceFinder Software:
First CDS to unify the workflows for chromatography and routine quantitative mass spectrometry (MS) analysis
Chromeleon Chromatography Data System (CDS) Software
First CDS to unify the workflows for chromatography and routine quantitative mass spectrometry (MS) analysis
Compound Discoverer Software:
Small molecule identification
Proteome Discoverer Software:
Comprehensive analysis of a wide range of proteomics workflows
For Research Use Only. Not for use in diagnostic procedures.
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