Basic life processes start in the cell, which is why biologists seek to understand how they function and respond to disease or genetic variations. Cellular biology explores individual cells and the ways in which they are organized into organs and tissues. Structural biology delves deeper into sub-cellular components, organelles and macromolecular structures. Electron microscopy (EM) is capable of providing insight at all these scales and more, revealing even atomic-level structural details for a range of biomolecules.

We’ve created this learning center to connect scientists around the world to the latest information on electron microscopy technology and to guide you to the best solution that will accelerate your next discovery or breakthrough.

Visit Electron Microscopy for the Life Sciences to learn more.

 

Learn from the experts

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Ask the Experts Series

These interactive Q&A sessions offer you the chance to stay connected to the latest science through conversations on unique topics.

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Podcast Series: Getting to know you

In this informal podcast series, we get to know some members of our scientific community and their latest work.                                                 

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On-demand webinars

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Single particle analysis webinars

Single particle analysis (SPA) is a cryo-electron microscopy technique that enables structural characterization at near-atomic resolutions, unraveling dynamic biological processes and the structure of biomolecular complexes/assemblies.          

Watch now to learn about structural biology at near-atomic resolution ›

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Cryo-tomography webinars

Cryo-electron tomography (cryo-ET) delivers both structural information about individual proteins as well as their spatial arrangements within the cell. Cryo-ET can bridge the gap between light microscopy and near-atomic-resolution techniques like single-particle analysis.

Watch now to see how cryo-ET is opening literal windows into cells ›

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MicroED webinars

Micro electron diffraction (MicroED) is an exciting new technique with applications in the structural determination of small molecules and protein. With this method, atomic details can be extracted from individual nanocrystals (<200 nm in size), even in a heterogeneous mixture. Watch now to see how

MicroED is transforming structure determination ›


Customer and expert interviews

Watch these interviews to learn how our customers and products are impacting the latest life science research.

Sars-CoV-2 research at UT-Austin

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Prof. Jason McLellan answers questions about spike protein structure, cryo-EM and vaccine trials with collaborators at NIH. Filmed in March 2020, video courtesy of The University of Texas at Austin.

Prof. Briegel and new discoveries in microbes with CryoET

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Prof. Ariane Briegel from Leiden University was plenary speaker at ASM Microbe 2019. She discusses how cryo-electron tomography is overcoming research barriers faced in microbiology and gives her top tips for working with the technology.

Prof. Villa and role of cryoET in Parkinson's research

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Prof. Elizabeth Villa from UCSD describes the role of cryo-tomography which brings structural biology to cell biology in order to look at structure and function of key proteins for better understanding of disease mechanisms.


New publications at the forefront of life science research

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Hervas, R. et al. Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila.
Science 367, 1230 (2020). DOI: 10.1126/science.aba3526

Hurdiss, D. L. et al. Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans.
bioRxiv (2020). DOI: 10.1101/2020.03.25.998963

Liang, Y.-L. et al. Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
ACS Pharmacol. Transl. Sci. (2020). DOI: 10.1021/acsptsci.9b00080

View list of publications ›


Learn cryo-EM essentials

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Visit EM-learning.com to learn about the foundations of cryo-EM, including the single particle analysis (SPA) workflow, via step-by-step instructions, expert demonstrations and theoretical lessons—at any pace, from any place and free of charge.

Visit EM-learning.com ›


Featured blog

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Our Accelerating Microscopy Blog offers educational content and the latest research highlights across disciplines. Be sure to read the featured post; "Cryo-EM Used in Novel Coronavirus Research to Support Vaccine, Treatment Development."

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Our events

Stay up to date on our virtual and physical events.

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View our Materials and Structural Analysis Webinars ›

 

Electron microscopy services for
the life sciences

To ensure optimal system performance, we provide you access to a world-class network of field service experts, technical support, and certified spare parts.

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