Basic life processes start in the cell, which is why biologists seek to understand how they function and respond to disease or genetic variations. Cellular biology explores individual cells and the ways in which they are organized into organs and tissues. Structural biology delves deeper into sub-cellular components, organelles and macromolecular structures. Electron microscopy (EM) is capable of providing insight at all these scales and more, revealing even atomic-level structural details for a range of biomolecules.

We’ve created this learning center to connect scientists around the world to the latest information on electron microscopy technology and to guide you to the best solution that will accelerate your next discovery or breakthrough.

Visit Electron Microscopy for the Life Sciences to learn more ›


Learn from the experts

On-demand webinars

Single particle analysis webinars

Single particle analysis (SPA) is a cryo-electron microscopy technique that enables structural characterization at near-atomic resolutions, unraveling dynamic biological processes and the structure of biomolecular complexes/assemblies.          

Watch now to learn about structural biology at near-atomic resolution ›

Cryo-tomography webinars

Cryo-electron tomography (cryo-ET) delivers both structural information about individual proteins as well as their spatial arrangements within the cell. Cryo-ET can bridge the gap between light microscopy and near-atomic-resolution techniques like single-particle analysis.

Watch now to see how cryo-ET is opening literal windows into cells ›

MicroED webinars

Micro electron diffraction (MicroED) is an exciting new technique with applications in the structural determination of small molecules and protein. With this method, atomic details can be extracted from individual nanocrystals (<200 nm in size), even in a heterogeneous mixture. Watch now to see how

MicroED is transforming structure determination ›


Customer and expert interviews

Watch these interviews to learn how our customers and products are impacting the latest life science research.

Dr. Erica Saphire on how cryo-EM is advancing her virus research

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Prof. Erica Ollmann Saphire from La Jolla Institute for Immunology discusses how cryo-EM has been a winner to understand a range of virus structures from Ebola to SARS-CoV-2 leading to insights for drugs and vaccine development.

Sars-CoV-2 research at UT-Austin

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Prof. Jason McLellan answers questions about spike protein structure, cryo-EM and vaccine trials with collaborators at NIH. Filmed in March 2020, video courtesy of The University of Texas at Austin.

Prof. Briegel and new discoveries in microbes with CryoET

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Prof. Ariane Briegel from Leiden University was plenary speaker at ASM Microbe 2019. She discusses how cryo-electron tomography is overcoming research barriers faced in microbiology and gives her top tips for working with the technology.


New publications at the forefront of life science research

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Shatter the limits of discovery! Use our publications search tool to access the latest life science research performed with cryo-EM. Subscribe to our monthly newsletter to receive a curated list of 4-5 recent publications.

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Learn cryo-EM essentials


Celebrating women in cryo-EM


Cryo-EM eBooks

Cryo-EM eBook

Cryo-EM can determine structures of challenging proteins without the need for crystals and can provide insights into how these proteins function in a way that other methods simply cannot. Use cryo-EM to get a broader picture of how membrane proteins function and contribute to disease to drive your research and improve drug design. Learn more about adopting cryo-EM and how it can advance your research. 

Download eBook

Tomography eBook

Access the inner workings of cells through 3D sample reconstruction at unprecedented nanoscale resolution. Results from this technique are having profound effects on our understanding of cell biology, revealing native cellular architecture with molecular clarity. Explore a curated collection of publications highlighting the use of cryo-ET. 

Download tomography eBook

Virology eBook

Cryo-EM technology is helping researchers overcome challenges related to virus purification and protein homogeneity and revolutionizing antiviral drug discovery and vaccine design. Learn more about how cryo-EM can help solve structural puzzles in virology. 

Download virology eBook


Get started with cryo-EM

Overcoming misperceptions about cryo-EM

Discover the facts behind the five most common misperceptions and learn how you can get started in cryo-EM. 

Download the infographic


Learn more about how cryo-EM works and how an accessible cryo-EM workflow can revolutionize your research. 

Learn more


Featured blog

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Our Accelerating Microscopy Blog offers educational content and the latest research highlights across disciplines. Be sure to read the featured post; "Cryo-EM Used in Novel Coronavirus Research to Support Vaccine, Treatment Development."

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Our events

Stay up to date on our virtual and physical events.

View our events ›
View our Materials and Structural Analysis Webinars ›

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