Streamlining Cryo-EM

for Tomography and Single Particle Analysis Workflows

November 20

Session 1: 10:00 a.m. CET

Session 2: 5:00 p.m. CET | 11 a.m. ET | 8 a.m. PT

 

In recent years, cryo-electron microscopy (cryo‐EM) single-particle analysis (SPA) has greatly benefited from a multitude of technological advances that have made it possible to image biological macromolecules at atomic resolution. Thanks to high throughput, high-resolution screening and data collection technologies, cryo-EM has delivered structural insights that are driving rational design of new vaccines and therapeutics. Cryo-electron tomography (cryo-ET) has been similarly important, enabling visualization of organelles and cellular structures in their near-native state within the cellular context at molecular resolution. Both techniques are indispensable tools for both structural and cell biology. 

 

In this webinar, we will present four innovative Thermo Scientific solutions that help improve the efficiency and performance of cryo-EM workflows and enhance connectivity between cryo-FIB and cryo-TEM:

  • Thermo Scientific Arctis Cryo-Plasma-FIB: high-throughput lamella preparation

  • Thermo Scientific Vacuum Capsule: optimized transfer of lamellae to the cryo-TEM without contamination

  • Thermo Scientific Krios 5 Cryo-TEM: quick, accurate, and efficient data collection

  • Thermo Scientific CryoTomo Software Suite: workflow automation, predictive tracking, rapid quality assessment, web platform, and more

     

Join us to learn how these cutting-edge technologies can improve the efficiency and performance of your cryo-EM workflows and see new application examples that demonstrate their capabilities.


About the speaker

Marc Storms, Thermo Fisher Scientific

Marc holds a PhD in virology and has been involved in the development, product management, and product marketing of various hardware and software solutions for (cryo) electron microscopy and its associated workflows. Platforms include the Thermo Scientific Vitrobot System, Krios Cryo-TEM, Arctis Cryo-TEM, Glacios Cryo-TEM, application software developments for SPA (EPU Software), and methods to enhance contrast and detector performance such as the Volta phase plate, the cold-FEG, several generations of cameras (Eagle), and Falcon Direct Electron Detectors.


Alex Rigort, Thermo Fisher Scientific

In addition to his work at Thermo Fisher, Alex holds a guest researcher position at the Max Planck Institute of Biochemistry in Martinsried, Germany. He has pioneered the use of cryo-focused ion beam instruments for cryo-tomography at the Max Planck Institute of Biochemistry and has long-standing experience in cryo-electron microscopy.


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