An All-In-One Process Raman Solution

Process Analyzers 

These compact and powerful Raman analyzers deliver accurate, actionable results enabling user-friendly, real-time process monitoring and control​​.

Process Raman Analyzers

The Thermo Scientific MarqMetrix All-In-One Process Raman Analyzer delivers reliable Raman data in real-time. You can use this solid-state analyzer across a variety of applications and with many sample types including solids, liquids, gases, powders, slurries, and heterogenous mixtures.

 

About the size of a textbook and with the ability to operate on its side, this small analyzer saves you valuable space; it’s easily installed anywhere from a crowded lab bench to process cabinets. 

The MarqMetrix BallProbe Sampling Optic technology utilizes an exclusively sourced, high-grade spherical sapphire lens. The short focal length of the spherical optic allows for simple TouchRaman Immersion Technology sampling. Users simply touch the probe to the sample and collect reproducible spectra of liquids, solids, slurries, powders, and heterogeneous mixtures. The MarqMetrix BallProbe Sampling Optic allows non-specialists to collect high-quality data and eliminates user-to-user variation.  

MarqMetrix Probes

These versatile families of probes are designed with patented technology to simplify sampling methods and meet rigorous industry needs.

Process Probes

The Thermo Scientific MarqMetrix Process BallProbe Sampling Optic is engineered for the most demanding environments. Constructed from Hastelloy C-276, this robust probe is designed to withstand exposure to harsh chemicals and extreme conditions such as high temperature, pressure, and corrosive conditions.

 

This probe is available in two standard diameters and various lengths for reliable sampling across rigorous environments.

Features and benefits 

  • Immersion contact probe for touch measurements
  • Samples liquids, solids, slurries, powders, and heterogeneous mixtures
  • Simple design for measurement accuracy and reproducibility
  • Designed to withstand challenging chemical, pressure, and temperature conditions

Performance Probes

The Thermo Scientific MarqMetrix Performance BallProbe Sampling Optic is built for moderate chemical environments in both laboratory and industrial settings. Featuring a large spherical sapphire ball lens and 316L stainless steel construction, it allows for easy and reproducible Raman measurements. 

 

Available in three standard diameters and various lengths, this probe offers versatile and reliable performance.

Features and benefits

  • Accurate and repeatable measurements
  • Samples liquids, solids, slurries, powders, and heterogeneous mixtures
  • Wide range of chemical compatibility and resistance to high-temperatures
  • Ease of use eliminates user-to-user variation

Bioreactor probes

The Thermo Scientific MarqMetrix BioReactor BallProbe Sampling Optic is purpose-built to monitor common bioreactor processes. Durable and autoclavable past 30+ autoclave cycles, this probe includes a standard Pg 13.5 threaded adapter for universal integration into bioreactor platforms such as the Thermo Scientific HyPerforma and DynaDrive bioreactor platforms. 

 

Built from 316L stainless steel, this probe allows for easy and reproducible Raman measurements across all sizes of bioreactors in your workflow. It’s available in multiple lengths for analysis in any bioreactor system from benchtop to production volumes.

Features and benefits

  • Accurate and repeatable measurements
  • Durable design, autoclavable (CIP/SIP)
  • Protective cap shields the probe's internal optics during autoclaving and storage
  • Compatible with standard Pg 13.5 ports
  • Easy to use, eliminates user-to-user variation

Single-Use Bioreactor probes

The MarqMetrix Single-Use BioReactor BallProbe Sampling Optic is specifically designed to monitor common bioreactor processes. This probe includes a standard Pg 13.5 threaded adapter for universal integration into bioreactor platforms such as the Thermo Scientific HyPerforma and DyndaDrive bioreactor platforms.

 

Built from 316L stainless steel, this probe allows for easy and reproducible Raman measurements across all sizes of bioreactors in your workflow in an easy to use single-use setup. The probe is available in multiple lengths for analysis in any bioreactor system from benchtop to production volumes.

This MarqMetrix Single Use BioReactor BallProbe Sampling Optic is ideal for biopharmaceutical and pharmaceutical manufacturing due to its accurate and reproducible measurements. The probe, which comes in tear-away bags, can be sterilized using an autoclave, steam-in-place (SIP), or EtO, or it can be incorporated into larger single-use systems and gamma sterilized. The sterile probe can easily be connected to the Raman system's fiber optic interface, enabling powerful real-time chemical insights. When the process is completed, the probe can simply be disposed of to ensure batch purity.

 

Features and benefits  

  • Single-use (disposable) Raman probe for high-value batches 
  • Accurate and repeatable measurement of liquids and solids  
  • Designed to be sterilized by autoclave, SIP, EtO, or gamma (probe does not come pre-sterilized)  
  • Compatible with standard Pg13.5 ports  
  • Customization available for integrators  

Other available ballprobe sampling optics:

  • MarqMetrix Performance BallProbe Sampling Optic
  • MarqMetrix Process BallProbe Sampling Optic
  • MarqMetrix Custom BallProbe Sampling Optic
  • MarqMetrix Fiber BallProbe Sampling Optic

MarqMetrix Proximal BallProbe High Volume (HV) Sampling Optic

The Proximal BallProbe HV excels at sampling from a distance and taking measurements of in-motion samples with varying heights. The probe’s long working distance (100mm) can rapidly analyze samples on conveyor belts or rotating drums. Its large sampling area (3.5mm) effectively averages the sample as you take measurements.

Features and benefits 

  • Non-contact analysis of:
    • Samples in motion
    • Samples with variable surface relief
    • Samples with uneven packaging
    • (e.g., pellets)
  • Compact design
    • 100mm working distance for measurement through windows, vials, and bags
    • Large depth of field for measurement of samples of variable size and/or surface thickness

FlowCell probes

The Thermo Scientific MarqMetrix FlowCell BallProbe Sampling Optic enables precise Raman measurements in a continuous flow setup. This probe is designed for seamless integration with industry-standard connections.

 

This probe is available in multiple flow path diameters and materials of construction, enabling integration in challenging process flow-through applications.

Features and benefits

  • BallProbe technology integrates directly into the flow path
  • Minimizes dead volume and sample handling requirements
  • Simple design for easy integration
  • Custom flow cell probes: Available with higher pressure/temperature ratings, different materials, custom connections, and internal volumes

Proximal probes

The Thermo Scientific MarqMetrix Proximal BallProbe Sampling Optic enables precise, real-time process monitoring without direct sample contact. This probe is ideal for samples in motion on conveyor belts and through clear physical barriers such as glass vials or windows. The specially engineered sapphire lens ensures a strong and clear Raman signal.

 

This probe is available in multiple sizes for different focal distances, enabling easy integration into processes without the need for contact.

Features and benefits

  • 8mm working distance for non-contact sampling through windows, vials, and bags
  • Compact design
  • High-signal throughput
  • Exceptional Raman signal in the fingerprint region
  • Can be coupled with the MarqMetrix All-In-One Process Analyzer for full spectral range measurements of 100-3250 cm-1

For Research Use Only. Not for use in diagnostic procedures.