Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.
B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 6 protein homolog; BCL5; BCL6; LAZ-3 protein; LAZ3; ZBTB27; ZNF51
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