Protein C is a vitamin K-dependent serine protease produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa and thus inhibits blood coagulation. The molecular weight of the active enzyme is 55kDa and the normal concentrations in human plasma is approximately 1-3 ng/ml because of the very fast turnover, the proenzyme concentration is approximately 3 µg/ml.
Activated blood coagulation factor XIV; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; prepro-protein C; protein C (inactivator of coagulation factors Va and VIIIa); type I protein C; Vitamin K dependent protein C precursor; Vitamin K-dependent protein C
Please enter the information below and press OK to send your cart to Core Services for purchase.