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This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
ANG-5; angiopoietin 5; angiopoietin like 3; Angiopoietin-5; angiopoietin-like 3; angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGPT5; ANGPTL3; ANGPTL3(17-221); ANGPTL3(17-224); ANL3; FHBL2; hypl; hypolipidemia; UNQ153/PRO179
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