ATG4D Antibodies

Target Information

Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein that localizes to the cytoplasm and belongs to the C-54 family of cysteine proteases. Expressed predominately in skeletal muscle, but also present in testis, Atg4D functions as a cysteine protease that is required for autophagy and functions to specifically cleave the C-terminal region of target proteins, thereby allowing the target proteins to bind to autophagosomes. The enzymatic activity of Atg4D is inhibited by Nethylmaleimide, a thiol reactive compound that is capable of modifying cystine residues in proteins and peptides.

Synonyms

9830134P12Rik; APG4 (ATG4) autophagy-related homolog D; APG4 autophagy 4 homolog D; APG4D; APG4-D; ATG4 autophagy related 4 homolog D; Atg4d; Atg4dl; Autl4; AUT-like 4 cysteine endopeptidase; AUT-like 4, cysteine endopeptidase; Autophagin-4; autophagy related 4D cysteine peptidase; autophagy related 4D, cysteine peptidase; autophagy-related 4D; autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; cysteine protease ATG4D; Cysteine protease ATG4D, mitochondrial; cysteine protease involved in autophagy; cysteine protease involved in autophagy APG4-D