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Product Details
PA5-28363
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 220 and 441 of Human ATG4D
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545839
Product Specific Information
Predicted reactivity: Mouse (95%), Rat (95%), Pig (97%), Bovine (98%).^M
^M
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein that localizes to the cytoplasm and belongs to the C-54 family of cysteine proteases. Expressed predominately in skeletal muscle, but also present in testis, Atg4D functions as a cysteine protease that is required for autophagy and functions to specifically cleave the C-terminal region of target proteins, thereby allowing the target proteins to bind to autophagosomes. The enzymatic activity of Atg4D is inhibited by Nethylmaleimide, a thiol reactive compound that is capable of modifying cystine residues in proteins and peptides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APG4 (ATG4) autophagy-related homolog D; APG4 autophagy 4 homolog D; ATG4 autophagy related 4 homolog D; AUT-like 4 cysteine endopeptidase; AUT-like 4, cysteine endopeptidase; Autophagin-4; autophagy related 4D, cysteine peptidase; autophagy-related 4D; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; Cysteine protease ATG4D; cysteine protease involved in autophagy; cysteine protease involved in autophagy APG4-D; HsAPG4D
Gene Aliases: 9830134P12Rik; APG4-D; APG4D; ATG4D; Atg4dl; AUTL4
UniProt ID: (Human) Q86TL0, (Mouse) Q8BGV9
Entrez Gene ID: (Human) 84971, (Mouse) 235040, (Rat) 686505
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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