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Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
calcium uniporter regulatory subunit MCUb, mitochondrial; CCDC109B; coiled-coil domain containing 109B; coiled-coil domain-containing protein 109B; MCUB; mitochondrial calcium uniporter dominant negative beta subunit; mitochondrial calcium uniporter regulatory subunit MCUb
100 µL
150 µL
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