CX3CR1/Albumin Antibodies

Target Information

CX3CR1 also known as chemokine receptor 1 or fractalkine receptor is a G-protein-coupled receptor primarily expressed on subsets of immune cells such as monocytes natural killer cells and T lymphocytes. It binds to the chemokine ligand CX3CL1 (fractalkine) which is unique due to its membrane-bound nature and participates in critical processes like leukocyte adhesion and migration. This receptor-ligand interaction is vital for immune surveillance inflammation and tissue repair. Dysregulation of CX3CR1 is linked to various pathological states including chronic inflammatory diseases and cancer metastasis. In research contexts CX3CR1 is studied for its role in neuroinflammation and cardiovascular diseases where its modulation could offer therapeutic benefits. Albumin on the other hand is a versatile protein found in blood plasma and is the most abundant protein in human serum. It is crucial for maintaining osmotic pressure and acts as a carrier molecule for numerous endogenous and exogenous substances including hormones vitamins and drugs. Albumin's ability to bind and transport various molecules makes it an essential player in drug delivery systems and it is widely used in formulations to enhance the pharmacokinetics and bioavailability of therapeutic agents. The interaction between albumin and other drug molecules is a significant factor in pharmacology influencing drug distribution and clearance from the body.

Synonyms

Chemokine receptor 1; Fractalkine receptor; Human albumin; Serum albumin