DLAT Antibodies

Antibodies that detect DLAT can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target DLAT in Human, Rat and Mouse samples. Our DLAT polyclonal, recombinant monoclonal and... Antibodies that detect DLAT can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target DLAT in Human, Rat and Mouse samples. Our DLAT polyclonal, recombinant monoclonal and monoclonal antibodies are... Antibodies that detect DLAT can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target DLAT in Human, Rat and Mouse samples. Our DLAT polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown and Relative expression to confirm specificity to DLAT. Find the DLAT antibody that fits your needs. Choose from 1 of 25 DLAT antibodies, which have been validated in experiments with 15 publications and 76 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with... Antibodies that detect DLAT can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target DLAT in Human, Rat and Mouse samples. Our DLAT polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown and Relative expression to confirm specificity to DLAT. Find the DLAT antibody that fits your needs. Choose from 1 of 25 DLAT antibodies, which have been validated in experiments with 15 publications and 76 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure.

Synonyms

6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2

DLAT Antibodies

Target Information

Synonyms

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