Anti-GCN1L1 Antibodies

GCN1L1 Antibodies

Antibodies that detect GCN1L1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target GCN1L1 in Human, Rat and Mouse samples. Our GCN1L1 polyclonal antibodies are developed in Rabbit. These antibodies have been verified by Relative expression to confirm specificity to GCN1L1. Find the GCN1L1 antibody that fits your needs. Choose from 1 of 6 GCN1L1 antibodies, which have been validated in experiments with 23 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification ... View more Antibodies that detect GCN1L1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target GCN1L1 in Human, Rat and Mouse samples. Our GCN1L1 polyclonal antibodies are developed in Rabbit. These antibodies have been verified by Relative expression to confirm specificity to GCN1L1. Find the GCN1L1 antibody that fits your needs. Choose from 1 of 6 GCN1L1 antibodies, which have been validated in experiments with 23 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Acts as a positive activator of the EIF2AK4/GCN2 protein kinase activity in response to amino acid starvation. Forms a complex with EIF2AK4/GCN2 on translating ribosomes; during this process, GCN1 seems to act as a chaperone to facilitate delivery of uncharged tRNAs that enter the A site of ribosomes to the tRNA-binding domain of EIF2AK4/GCN2, and hence stimulating EIF2AK4/GCN2 kinase activity. Participates in the repression of global protein synthesis and in gene-specific mRNA translation activation, such as the transcriptional activator ATF4, by promoting the EIF2AK4/GCN2-mediated phosphorylation of eukaryotic translation initiation factor 2 (eIF-2-alpha/EIF2S1) on 'Ser-52', and hence allowing ATF4-mediated reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion. [UniProt]

Synonyms

4932409G22; AL022764; eIF-2-alpha kinase activator GCN1; G431004K08Rik; Gcn1; GCN1 (general control of amino-acid synthesis 1, yeast)-like 1; GCN1 eIF2 alpha kinase activator homolog; GCN1 eIF-2-alpha kinase activator homolog; GCN1 general control of amino-acid synthesis 1-like 1; GCN1 general control of amino-acid synthesis 1-like 1 (yeast); GCN1, eIF2 alpha kinase activator homolog; GCN1L; GCN1L1; GCN1-like protein 1; General control of amino-acid synthesis 1-like protein 1; hsGCN1; KIAA0219; mKIAA0219; peroxisome proliferator activated receptor interacting complex protein; PRIC295; translational activator GCN1

GCN1L1 Antibodies

Target Information

Synonyms

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