HGS Antibodies

Antibodies that detect HGS can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target HGS in Human, Mouse, Rat, Canine and Feline samples. Our HGS polyclonal, monoclonal and... Antibodies that detect HGS can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target HGS in Human, Mouse, Rat, Canine and Feline samples. Our HGS polyclonal, monoclonal and recombinant monoclonal... Antibodies that detect HGS can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target HGS in Human, Mouse, Rat, Canine and Feline samples. Our HGS polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the HGS antibody that fits your needs. Choose from 1 of 24 HGS antibodies, which have been validated in experiments with 16 publications and 59 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody... Antibodies that detect HGS can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and ELISA. These antibodies target HGS in Human, Mouse, Rat, Canine and Feline samples. Our HGS polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the HGS antibody that fits your needs. Choose from 1 of 24 HGS antibodies, which have been validated in experiments with 16 publications and 59 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

HGS is involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. It could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. HGS may concentrate ubiquitinated receptors within clathrin-coated regions. It is involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM. This complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. HGS may contribute to the efficient recruitment of SMADs to the activin receptor complex.

Synonyms

hepatocyte growth factor-regulated tyrosine kinase substrate; HGF-regulated tyrosine kinase substrate; HGNC:4897; Hgr; Hgs; Hrs; Hrs2; human growth factor-regulated tyrosine kinase substrate; protein pp110; SNAP-25-interacting protein Hrs-2; ZFYVE8

HGS Antibodies

Target Information

Synonyms

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