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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 611 and 777 of Human HGS|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27491 targets HGS in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-27491 immunogen is recombinant fragment corresponding to a region within amino acids 611 and 777 of Human HGS.
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Hepatocyte growth factor-regulated tyrosine kinase substrate; HGF-regulated tyrosine kinase substrate; HRS; human growth factor-regulated tyrosine kinase substrate; Protein pp110; SNAP-25-interacting protein Hrs-2
Hgr; HGS; HRS; Hrs2; ZFYVE8