HLA-DOA Antibodies

Antibodies that detect HLA-DOA can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target HLA-DOA in Human, Mouse and Rat samples. Our HLA-DOA polyclonal antibodies are developed in... Antibodies that detect HLA-DOA can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target HLA-DOA in Human, Mouse and Rat samples. Our HLA-DOA polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been... Antibodies that detect HLA-DOA can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target HLA-DOA in Human, Mouse and Rat samples. Our HLA-DOA polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression to confirm specificity to HLA-DOA. Find the HLA-DOA antibody that fits your needs. Choose from 1 of 8 HLA-DOA antibodies, which have been validated in experiments with 13 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to... Antibodies that detect HLA-DOA can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target HLA-DOA in Human, Mouse and Rat samples. Our HLA-DOA polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression to confirm specificity to HLA-DOA. Find the HLA-DOA antibody that fits your needs. Choose from 1 of 8 HLA-DOA antibodies, which have been validated in experiments with 13 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Reacts with HLA-DO, a heterodimer formed by DNalpha and DObeta subunits in B cells. DNalpha and DObeta are the products of the non-classical class II genes, HLA-DNA and HLA-DOB, respectively. DO forms tight complexes with DM in the endoplasmic reticulum and is thereby sorted to lysosomal vesicles during antigen processing and presentation. It is tightly associated with DM and it is selectively expressed on antigen-presenting cells, such as B cells, dendritic cells and thymic epithelial cells. DO can enhance the efficiency of peptide loading and has been found to stabilize DM at low pH, preserving its chaperon activity. DO-DM complexes are more efficient than DM in protecting empty DR molecules. Reports describe DO as a co-chaperone of DM. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Synonyms

HLA class II histocompatibility antigen, DO alpha chain; HLA-D0-alpha; HLA-DNA; HLA-DOA; HLADZ; HLA-DZA; lymphocyte antigen; major histocompatibility complex, class II, DN alpha; major histocompatibility complex, class II, DO alpha; MHC class II antigen DOA; MHC DN-alpha; MHC DZ alpha

HLA-DOA Antibodies

Target Information

Synonyms

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