HuC/HuD Antibodies

Target Information

Anti-Hu antibodies were originally isolated from a patient with paraneoplastic encephalomyelitis, a rare condition of selective neural tissue injury associated with small cell lung carcinoma. The antibodies bind specifically to antigens present exclusively in neuronal cells and are thus useful as markers of neuronal cells in tissue. The Hu antigen is an RNA-binding protein of the embryonic lethal abnormal visual (Elav) family.

Synonyms

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV like neuron-specific RNA binding protein 3; ELAV like neuron-specific RNA binding protein 4; ELAV like RNA binding protein 4; elavC; ELAVL3; elavl3 protein; elavl4; ELAV-like protein 3; ELAV-like protein 4; elav-related C; elav-related D; elrc; elrd; embryonic lethal, abnormal vision-related C; embryonic lethal, abnormal vision-related D; etID309927.3; Hu antigen C; Hu antigen D; hu-antigen C; Hu-antigen D; HuC; HUCL; hud; id:ibd1248; Paraneoplastic cerebellar degeneration-associated antigen; paraneoplastic encephalomyelitis antigen HuD; Paraneoplastic limbic encephalitis antigen 21; PLE21; PNEM; protein elrD; ribonucleoprotein; RNA-binding protein HuD; wu:fb77b03; wu:fc24h01; zHuC