JAK2 Antibodies

Antibodies that detect JAK2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, ELISA and Immunocytochemistry. These antibodies target JAK2 in Human, Mouse, Rat, Zebrafish and Porcine samples. Our JAK2 polyclonal, recombinant... Antibodies that detect JAK2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, ELISA and Immunocytochemistry. These antibodies target JAK2 in Human, Mouse, Rat, Zebrafish and Porcine samples. Our JAK2 polyclonal, recombinant monoclonal, monoclonal and recombinant... Antibodies that detect JAK2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, ELISA and Immunocytochemistry. These antibodies target JAK2 in Human, Mouse, Rat, Zebrafish and Porcine samples. Our JAK2 polyclonal, recombinant monoclonal, monoclonal and recombinant superclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment to confirm specificity to JAK2. Find the JAK2 antibody that fits your needs. Choose from 1 of 73 JAK2 antibodies, which have been validated in experiments with 82 publications and 159 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.... Antibodies that detect JAK2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, ELISA and Immunocytochemistry. These antibodies target JAK2 in Human, Mouse, Rat, Zebrafish and Porcine samples. Our JAK2 polyclonal, recombinant monoclonal, monoclonal and recombinant superclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment to confirm specificity to JAK2. Find the JAK2 antibody that fits your needs. Choose from 1 of 73 JAK2 antibodies, which have been validated in experiments with 82 publications and 159 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains the catalytic domain (JH1) of JAK2. The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus. Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes. JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier. Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex. Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Synonyms

EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

JAK2 Antibodies

Target Information

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