Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. The alpha- and beta-synuclein proteins are found primarily in brain tissue, where they are seen mainly in presynaptic terminals. The gamma-synuclein protein is found primarily in the peripheral nervous system and retina, but its expression in breast tumors makes it a candidate as a marker for tumor progression.
Alpha-synuclein; NACP; Non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; Snca; synuclein alpha