Positive Control: mouse brain, rat brain
Predicted Reactivity: Human (93%), Xenopus laevis (84%), Pig (92%), Chicken (87%), Sheep (91%), Chimpanzee (93%), Bovine (91%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. The alpha- and beta-synuclein proteins are found primarily in brain tissue, where they are seen mainly in presynaptic terminals. The gamma-synuclein protein is found primarily in the peripheral nervous system and retina, but its expression in breast tumors makes it a candidate as a marker for tumor progression.
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Protein Aliases: Alpha-synuclein; NACP; Non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; Snca; synuclein alpha
Gene Aliases: alphaSYN; NACP; Snca; Syn