RNASE7 Antibodies

Antibodies that detect RNASE7 can be used in several scientific applications, including Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target RNASE7 in Human and Rat samples. Our RNASE7 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit.... Antibodies that detect RNASE7 can be used in several scientific applications, including Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target RNASE7 in Human and Rat samples. Our RNASE7 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the RNASE7 antibody that fits your... Antibodies that detect RNASE7 can be used in several scientific applications, including Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target RNASE7 in Human and Rat samples. Our RNASE7 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the RNASE7 antibody that fits your needs. Choose from 1 of 4 RNASE7 antibodies, which have been validated in experiments with 20 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for,... Antibodies that detect RNASE7 can be used in several scientific applications, including Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target RNASE7 in Human and Rat samples. Our RNASE7 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the RNASE7 antibody that fits your needs. Choose from 1 of 4 RNASE7 antibodies, which have been validated in experiments with 20 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The RNASE7 gene encodes a ribonuclease enzyme characterized by its potent ribonucleolytic activity and antimicrobial properties. It is part of the RNase A superfamily, featuring eight conserved cysteines and a catalytic histidine-lysine-histidine triad. RNase 7 is expressed in various somatic tissues, including the liver, kidney, skeletal muscle, and heart, and is prominently found in the stratum corneum of human skin. Its role is crucial in innate immune defense, assisting in the high resistance of human skin against infections. The expression of RNASE7 can be significantly induced by pro-inflammatory cytokines such as interferon-?, interleukin 1ß, and to a lesser extent by tumor necrosis factor-a. This induction highlights its role in immune responses. Beyond its antimicrobial activity, RNase 7 has been shown to play a role in translating self-nucleic acids into TLR9 activators, influencing the DNA-mediated activation of immune cells like keratinocytes. These functions underscore RNASE7's significance in both maintaining skin barrier function and modulating immune responses.

Synonyms

RAE1; Ribonuclease 7; ribonuclease A family member 7; ribonuclease, RNase A family, 7; RNase 7; RNASE7; SAP-2; skin-derived antimicrobial protein 2; UNQ2516/PRO6006

RNASE7 Antibodies

Target Information

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