Antibodies that detect SCK can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry (Paraffin) and Immunohistochemistry (Frozen). These antibodies target SCK in Human, Rat and Mouse samples. Our SCK polyclonal antibodies are developed in Rabbit. Find the SCK antibody that fits your needs. Choose from 1 of 5 SCK antibodies, which have been validated in experiments with 8 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
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Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events. Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain. Human Sck transcripts are present at high levels in liver, pancreas, prostate and ovary. In vascular endothelial cells, Sck participates in VEGF-induced signal transduction. Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation.
neuronal Shc adaptor homolog; Protein Sck; SH2 domain protein C2; SHC (Src homology 2 domain containing) transforming protein 2; SHC-transforming protein 2; SHC-transforming protein B; src homology 2 domain-containing transforming protein C2; Src homology 2 domain-containing-transforming protein C2
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