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TLR4 (CD284) Antibodies

Antibodies that detect TLR4 (CD284) can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target TLR4 (CD284) in Human, Mouse, Rat, Canine and Porcine samples. Our TLR4 (CD284) monoclonal, polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Mouse, Rabbit, Rat and Goat. These antibodies have been verified by Cell treatment, Knockdown and Knockout to confirm specificity to TLR4 (CD284). Find the TLR4 (CD284) antibody that fits your needs. Choose from 1 of 63 TLR4 (CD284) antibodies, which have been validated in experiments with 1253 ... View more Antibodies that detect TLR4 (CD284) can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target TLR4 (CD284) in Human, Mouse, Rat, Canine and Porcine samples. Our TLR4 (CD284) monoclonal, polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Mouse, Rabbit, Rat and Goat. These antibodies have been verified by Cell treatment, Knockdown and Knockout to confirm specificity to TLR4 (CD284). Find the TLR4 (CD284) antibody that fits your needs. Choose from 1 of 63 TLR4 (CD284) antibodies, which have been validated in experiments with 1253 publications and 551 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. Mammalian cells respond to LPS by activating TLR4. TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. Mutations in the TLR4 gene have been associated with differences in LPS responsiveness. Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain. TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

Synonyms

ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Target Video

6320273625112

TLR4 (CD284) antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/a36ddbda-52b6-4b11-99c6-bc81e3a212da/2bffcdcc-d71f-474d-8fd5-b29f670b06fb/320x180/match/image.jpg

Learn more about TLR4 (CD284) primary antibodies that can be used in Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry in Human, Mouse, Rat and Dog samples.