Anti-TRAIL-R2 (DR5) Antibodies

Products
Images
Epitopes
New
Building a flow cytometry panel? Try Panel Builder

TRAIL-R2 (DR5) Antibodies

Antibodies that detect TRAIL-R2 (DR5) can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target TRAIL-R2 (DR5) in Human, Mouse and Rat samples. Our TRAIL-R2 (DR5) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Armenian Hamster. These antibodies have been verified by Cell treatment and Knockdown to confirm specificity to TRAIL-R2 (DR5). Find the TRAIL-R2 (DR5) antibody that fits your needs. Choose from 1 of 49 TRAIL-R2 (DR5) antibodies, which have been validated in experiments with 105 publications and 164 images featured ... View more Antibodies that detect TRAIL-R2 (DR5) can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target TRAIL-R2 (DR5) in Human, Mouse and Rat samples. Our TRAIL-R2 (DR5) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Armenian Hamster. These antibodies have been verified by Cell treatment and Knockdown to confirm specificity to TRAIL-R2 (DR5). Find the TRAIL-R2 (DR5) antibody that fits your needs. Choose from 1 of 49 TRAIL-R2 (DR5) antibodies, which have been validated in experiments with 105 publications and 164 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

DR5 (Apo2, TRAIL-R2, TRICK2, KILLER) is a recently identified death domain containing receptor for TRAIL, which mediates TRAIL induced apoptosis. DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain. DR5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by DR5. Two transcript variants encoding different isoforms of DR5 and one non-coding transcript have been found. Overexpression of DR5 induces apoptosis and activates NF-kappa-B. DR5 is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen. Diseases associated with DR5 dysfunction include squamous cell carcinoma, and diffuse infiltrative lymphocytosis syndrome.

Synonyms

apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9

Target Video

6320271545112

TRAIL-R2 (DR5) antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/974387bc-5d1a-40a3-86c8-a1d2d7f5ab2d/0386c0fc-a53f-45b1-be5d-bda0b48bc890/160x90/match/image.jpg

Learn more about TRAIL-R2 (DR5) primary antibodies that can be used in Immunohistochemistry, Western Blot, ELISA and Flow Cytometry in Human, Mouse and Rat samples.