Antibodies that detect TRBP can be used in several scientific applications, including Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Flow Cytometry and Peptide array. These antibodies target TRBP in Human, Mouse, Rat, Non-human primate and Equine samples. Our TRBP monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Knockdown and Knockout to confirm specificity to TRBP. Find the TRBP antibody that fits your needs. Choose from 1 of 18 TRBP antibodies, which have been validated in experiments with 17 publications and 85 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
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TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
PRM-1 RNA-binding protein; Protamine-1 RNA-binding protein; RISC-loading complex subunit TARBP2; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; TAR (HIV-1) RNA binding protein 2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TARBP2; trans-activation responsive RNA-binding protein; Trans-activation-responsive RNA-binding protein
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