|Tested species reactivity||Horse, Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (344 REAARGEAARRALQ 357) of TRBP protein.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5-10 µg/ml|
|Western Blot (WB)||5-8 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
TRBP is an RNA associated nuclear protein. It contains 3 DRBM (double stranded RNA-binding) domains and plays an important role by binding to HIV-1 TAR RNA located in the long terminal repeat (LTR). TRBP acts synergistic with viral TAT protein in HIV-1 expression activation. It binds preferentially to TAR and other double-stranded RNAs with G+C-rich characteristics. It is important in regulation of transcription from RNA polymerase II promoter and is widely expressed in most of the tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.