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Proteintech
SNAP25 Monoclonal Antibody (3E4B7)
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Product Details
60159-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3E4B7
Immunogen
SNAP25 Fusion Protein Ag6695 (1-206 aa encoded by BC010647)
Conjugate
Form
Liquid
Concentration
1.61 mg/mL
Amount
241.5 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAEDADMRN ELEEMQRRAD QLADESLEST RRMLQLVEES KDAGIRTLVM LDEQGEQLDR VEEGMNHINQ DMKEAEKNLK DLGKCCGLFI CPCNKLKSSD AYKKAWGNNQ DGVVASQPAR VVDEREQMAI SGGFIRRVTN DARENEMDEN LEQVSGIIGN LRHMALDMGN EIDTQNRQID RIMEKADSNK TRIDEANQRA TKMLGSG (1-206 aa encoded by BC010647)
Target Information
SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ALMS1; blind drunk; CG17676; CG17884; CG40452; Dmel CG40452; Dmel_CG40452; FLJ23079; HGNC:11132; HUMSNAP25B(F); resistance to inhibitors of cholinesterase 4 homolog; SNAP 25; SNAP-25; snp25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa; unnamed protein product
Gene Aliases: bA416N4.2; Bdr; CMS18; DEE117; dJ1068F16.2; GENA70; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SNAP-25a; SNAP-25B; SNAP25; sp; SUP
UniProt ID: (Human) P60880, (Rat) P70557, (Mouse) P60879
Entrez Gene ID: (Human) 6616, (Pig) 100620588, (Rat) 25012, (Mouse) 20614
neurotransmitter uptake
exocytosis
chemical synaptic transmission
neurotransmitter secretion
locomotory behavior
associative learning
regulation of neuron projection development
synaptic vesicle exocytosis
synaptic vesicle docking
synaptic vesicle priming
synaptic vesicle fusion to presynaptic active zone membrane
regulation of insulin secretion
long-term synaptic potentiation
regulation of establishment of protein localization
potassium ion transmembrane transport
presynaptic dense core vesicle exocytosis
axonogenesis
long-term memory
endosomal transport
growth hormone secretion
sleep
positive regulation of insulin secretion
positive regulation of hormone secretion
calcium ion-regulated exocytosis of neurotransmitter
regulation of synapse assembly
regulation of ion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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