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Proteintech
SNAP25 Monoclonal Antibody (3E4B7), CoraLite® Plus 488
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CL48860159100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3E4B7
Conjugate
CoraLite® Plus 488
CoraLite® Plus 488
CoraLite® Plus 488
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALMS1; blind drunk; CG17676; CG17884; CG40452; Dmel CG40452; Dmel_CG40452; FLJ23079; HGNC:11132; HUMSNAP25B(F); resistance to inhibitors of cholinesterase 4 homolog; SNAP 25; SNAP-25; snp25; SUP; super protein; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa; unnamed protein product
Gene Aliases: bA416N4.2; Bdr; CMS18; DEE117; dJ1068F16.2; GENA70; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SNAP-25a; SNAP-25B; sp; SUP
UniProt ID: (Human) P60880, (Mouse) P60879, (Rat) P60881
Entrez Gene ID: (Human) 6616, (Pig) 100620588, (Mouse) 20614, (Rat) 25012
neurotransmitter uptake
exocytosis
vesicle fusion
chemical synaptic transmission
neurotransmitter secretion
regulation of neuron projection development
synaptic vesicle exocytosis
synaptic vesicle priming
synaptic vesicle fusion to presynaptic active zone membrane
regulation of insulin secretion
regulation of establishment of protein localization
potassium ion transmembrane transport
presynaptic dense core vesicle exocytosis
long-term memory
locomotory behavior
associative learning
endosomal transport
insulin secretion
positive regulation of vesicle fusion
positive regulation of synaptic plasticity
SNARE complex assembly
positive regulation of hormone secretion
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of synaptic transmission
long-term synaptic potentiation
membrane fusion
clathrin-mediated endocytosis
regulation of synaptic vesicle cycle
positive regulation of voltage-gated calcium channel activity
positive regulation of glutamate secretion, neurotransmission
short-term synaptic potentiation
axonogenesis
neuron differentiation
positive regulation of insulin secretion
regulation of synapse assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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