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Proteintech
Annexin V Monoclonal Antibody (1E6A8)
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Product Details
66245-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1E6A8
Immunogen
Annexin V Fusion Protein Ag1538 (1-320 aa encoded by BC001429)
Conjugate
Form
Liquid
Concentration
0.93 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAQVLRGTV TDFPGFDERA DAETLRKAMK GLGTDEESIL TLLTSRSNAQ RQEISAAFKT LFGRDLLDDL KSELTGKFEK LIVALMKPSR LYDAYELKHA LKGAGTNEKV LTEIIASRTP EELRAIKQVY EEEYGSSLED DVVGDTSGYY QRMLVVLLQA NRDPDAGIDE AQVEQDAQAL FQAGELKWGT DEEKFITIFG TRSVSHLRKV FDKYMTISGF QIEETIDRET SGNLEQLLLA VVKSIRSIPA YLAETLYYAM KGAGTDDHTL IRVMVSRSEI DLFNIRKEFR KNFATSLYSM IKGDTSGDYK KALLLLCGED D (1-320 aa encoded by BC001429)
Target Information
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anchorin CII; Annexin A5; Annexin V; Annexin-5; anticoagulant precursor (5' end put.); putative; ANXA5; Calphobindin I; CBP-I; CPB-I; Endonexin II; epididymis secretory protein Li 7; Lipocortin V; lipocortin-V; PAP-I; Placental anticoagulant protein 4; Placental anticoagulant protein I; PP4; Thromboplastin inhibitor; unnamed protein product; VAC-alpha; Vascular anticoagulant-alpha
Gene Aliases: ANX5; ANXA5; CPB-I; ENX2; HEL-S-7; PP4; R74653; RPRGL3; VAC-alph
UniProt ID: (Human) P08758, (Mouse) P48036
Entrez Gene ID: (Human) 308, (Mouse) 11747
signal transduction
blood coagulation
hemostasis
negative regulation of apoptotic process
negative regulation of coagulation
positive regulation of defense response to virus by host
response to organic substance
negative regulation of blood coagulation
positive regulation of apoptotic process
protein homooligomerization
response to calcium ion
mitophagy in response to mitochondrial depolarization
regulation of sperm motility
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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