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Proteintech
NHEJ1 Monoclonal Antibody (1F8C7)
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Product Details
66552-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1F8C7
Immunogen
NHEJ1 Fusion Protein Ag2496 (1-299 aa encoded by BC030986)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEELEQGLL MQPWAWLQLA ENSLLAKVFI TKQGYALLVS DLQQVWHEQV DTSVVSQRAK ELNKRLTAPP AAFLCHLDNL LRPLLKDAAH PSEATFSCDC VADALILRVR SELSGLPFYW NFHCMLASPS LVSQHLIRPL MGMSLALQCQ VRELATLLHM KDLEIQDYQE SGATLIRDRL KTEPFEENSF LEQFMIEKLP EACSIGDGKP FVMNLQDLYM AVTTQEVQVG QKHQGAGDPH TSNSASLQGI DSQCVNQPEQ LVSSAPTLSA PEKESTGTSG PLQRPQLSKV KRKKPRGLFS (1-299 aa encoded by BC030986)
Target Information
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ12610; Non-homologous end-joining factor 1; nonhomologous end-joining factor 1; Protein cernunnos; unnamed protein product; XRCC4-like factor
Gene Aliases: IMD124; MCOPCB13; NHEJ1; XLF
UniProt ID: (Human) Q9H9Q4
Entrez Gene ID: (Human) 79840
telomere maintenance
DNA repair
double-strand break repair
double-strand break repair via nonhomologous end joining
cellular response to DNA damage stimulus
central nervous system development
response to ionizing radiation
B cell differentiation
T cell differentiation
immunoglobulin V(D)J recombination
positive regulation of ligase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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