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Antibodies Inc
Kv1.4 K+ Channel Monoclonal Antibody (K13/31), FL490
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Product Details
75-010-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
K13/31
Immunogen
Synthetic peptide 13-37 of rat Kv1.4 (NSHMPYGYAAQARARERERLAHSR; accession number P15385).
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Potassium voltage-gated channel subfamily A member 4, also known as Kv1.4 or PCN2, is a protein that in humans is encoded by the KCNA4 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It is mapped to 11p14.1. KCNA4 belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential. KCNA4 also contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. This gene has been shown to interact with DLG4, KCNA2 and DLG1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac potassium channel; fetal skeletal muscle potassium channel; HPCN2; potassium channel 2; potassium channel, voltage gated shaker related subfamily A, member 4; potassium voltage gated channel, shaker related subfamily, member 4; Potassium voltage-gated channel subfamily A member 4; potassium voltage-gated channel, shaker-related subfamily, member 4; rapidly inactivating potassium channel; RCK4; RHK1; RK3; shaker-related potassium channel Kv1.4; type A potassium channel; Voltage-gated K(+) channel HuKII; Voltage-gated potassium channel HBK4; Voltage-gated potassium channel HK1; Voltage-gated potassium channel subunit Kv1.4
Gene Aliases: HBK4; HK1; HPCN2; HUKII; KCHAN; KCNA4; KCNA4L; KCNA8; KV1.4; Kv4; MCIDDS; PCN2; RHK1; RK3
UniProt ID: (Human) P22459, (Rat) P15385, (Mouse) Q61423
Entrez Gene ID: (Human) 3739, (Rat) 25469, (Mouse) 16492
ion channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
potassium channel activity
protein binding
potassium ion binding
voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
voltage-gated ion channel activity
voltage-gated ion channel
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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