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Antibodies Inc
DLX1 Monoclonal Antibody (L43/40), FL550
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Product Details
75-078-FL550
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
L43/40
Immunogen
Synthetic peptide amino acids 53-74 of human DLX1 (accession number P56177).
Conjugate
Excitation/Emission Max
550/575 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: PDGAYSSASS FSRPLGYPYV NS
Target Information
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-beta superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DII B; distal-less homeo box 1; homeobox Dlx1; Homeobox protein DLX-1
Gene Aliases: Dlx; Dlx-1; DLX1
UniProt ID: (Human) P56177, (Mouse) Q64317
Entrez Gene ID: (Human) 1745, (Rabbit) 100348143, (Mouse) 13390, (Rat) 296500
negative regulation of transcription from RNA polymerase II promoter
proximal/distal pattern formation
subpallium development
hippocampus development
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
cerebral cortex GABAergic interneuron fate commitment
odontogenesis of dentin-containing tooth
negative regulation of neuron apoptotic process
negative regulation of Notch signaling pathway
embryonic skeletal system development
negative regulation of oligodendrocyte differentiation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
forebrain neuron differentiation
cerebral cortex GABAergic interneuron differentiation
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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