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Antibodies Inc
FGF13/FHF2/B Isoform Monoclonal Antibody (N225A/10), FL490
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Product Details
75-248-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
N225A/10
Immunogen
Synthetic peptide amino acids 1-20 of human FHF2B (accession number Q92913-2).
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: MALLRKSYSE PQLKGIVTKL
Target Information
FGF13B is an isoform of the fibroblast growth factor 13 (FGF13) protein, which belongs to the intracellular FGF family. This isoform plays a crucial role in the regulation of ion channels, neuronal development, and intracellular signaling pathways. Dysregulation of FGF13B has been implicated in various neurological conditions, including intellectual disabilities and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF-13; FHF-2; FHF2-1A; FHF2-1B; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; hFHF-2(1X+1W+1V); hFHF-2(1Z+1Y); unnamed protein product
Gene Aliases: DEE90; FGF-13; FGF13; FGF2; FHF-2; FHF2; LINC00889; XLID110
UniProt ID: (Human) Q92913
Entrez Gene ID: (Human) 2258
MAPK cascade
neuron migration
sodium ion transport
negative regulation of microtubule depolymerization
signal transduction
cell-cell signaling
nervous system development
learning or memory
learning
memory
hippocampus development
cerebral cortex cell migration
neurogenesis
establishment of neuroblast polarity
microtubule polymerization
negative regulation of collateral sprouting
branching morphogenesis of a nerve
protein localization to plasma membrane
regulation of cardiac muscle cell action potential involved in regulation of contraction
inhibitory synapse assembly
positive regulation of voltage-gated sodium channel activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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