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Antibodies Inc
TRAK1 Monoclonal Antibody (N389/9), FL650
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Product Details
75-371-FL650
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
N389/9
Immunogen
Fusion protein amino acids 1-110 (N-terminus) of human TRAK1 (accession number Q9UPV9) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
655/676 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes. TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 106 kDa O-GlcNAc transferase-interacting protein; milton homolog 1; O-linked N-acetylglucosamine transferase interacting protein 106; OGT(O-Glc-NAc transferase)-interacting protein 106 KDa; Protein Milton; Trafficking kinesin-binding protein 1; trafficking protein, kinesin binding 1; unnamed protein product
Gene Aliases: DEE68; EIEE68; KIAA1042; MILT1; OIP106; RGD1307844; TRAK1
UniProt ID: (Human) Q9UPV9
Entrez Gene ID: (Human) 22906, (Rat) 316085
regulation of transcription from RNA polymerase II promoter
protein O-linked glycosylation
protein targeting
endosome to lysosome transport
axonal transport of mitochondrion
neurogenesis
vesicle transport along microtubule
mitochondrion distribution
dendrite morphogenesis
positive regulation of axonogenesis
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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