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Antibodies Inc
NPY2R Monoclonal Antibody (L119/106)
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Product Details
75-460
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
L119/106
Immunogen
Fusion protein amino acids 1-51 (extracellular N-terminus) and 330-381 (cytoplasmic C-terminus) of human NPY2R, produced recombinantly in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC124241; MGC124242; MGC124244; Neuropeptide Y receptor type 2; neuropeptide Y receptor Y2-like; Neuropeptide y-y2; neuropeptide Y-Y2 receptor; neuropeptide Y/peptide YY-Y2 receptor; NPY-Y2 receptor; NPY2-R; Y2 receptor
Gene Aliases: NPY2-R; NPY2R
UniProt ID: (Human) P49146, (Mouse) P97295
Entrez Gene ID: (Human) 4887, (Mouse) 18167, (Rat) 66024
behavioral fear response
positive regulation of peptide secretion
outflow tract morphogenesis
cardiac left ventricle morphogenesis
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
nitric oxide mediated signal transduction
locomotory behavior
positive regulation of cell-substrate adhesion
negative regulation of neurological system process
positive regulation of dopamine secretion
positive regulation of smooth muscle contraction
positive regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of synaptic transmission
negative regulation of secretion
negative regulation of synaptic transmission, glutamatergic
negative regulation of excitatory postsynaptic potential
synaptic signaling via neuropeptide
negative regulation of cAMP/PKA signal transduction
negative regulation of feeding behavior
chemical synaptic transmission
negative regulation of cAMP biosynthetic process
secretion
regulation of sensory perception of pain
positive regulation of cell adhesion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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