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Proteintech
RNF31/HOIP Recombinant Rabbit Monoclonal Antibody (230446H1)
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Product Details
83137-3-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
230446H1
Immunogen
RNF31 / HOIP fusion protein Ag34505
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RDCLFYLRDW TALRLQKLLQ DNNVMFNTEP PAGARAVPGG GCRVIEQKEV PNGLRDEACG KETPAGYAGL CQAHYKEYLV SLINAHSLDP ATLYEVEELE TATERYLHVR PQPLAGEDPP AYQARLLQKL TEEVPLGQSI PRRRK
Target Information
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase RNF31; FLJ23501; HOIL-1-interacting protein; HOIP; MGC19975; RING finger protein 31; RING-type E3 ubiquitin transferase RNF31; unnamed protein product; Zinc in-between-RING-finger ubiquitin-associated domain protein
Gene Aliases: HOIP; IMD115; Paul; RNF31; ZIBRA
UniProt ID: (Human) Q96EP0
Entrez Gene ID: (Human) 55072
ubiquitin-protein transferase activity
protein binding
zinc ion binding
transferase activity
ubiquitin protein ligase binding
K48-linked polyubiquitin binding
identical protein binding
ubiquitin binding
metal ion binding
ubiquitin protein ligase activity
K63-linked polyubiquitin binding
linear polyubiquitin binding
protein polyubiquitination
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
protein ubiquitination
CD40 signaling pathway
defense response to bacterium
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
negative regulation of necroptotic process
protein linear polyubiquitination
positive regulation of protein targeting to mitochondrion
positive regulation of xenophagy
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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