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Proteintech
Geminin Recombinant Rabbit Monoclonal Antibody (240835B5)
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Product Details
84199-2-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
240835B5
Immunogen
Geminin fusion protein Ag1076
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MNPSMKQKQ EEIKENIKNS SVPRRTLKMI QPSASGSLVG RENELSAGLS KRKHRNDHLT STTSSPGVIV PESSENKNLG GVTQESFDLM IKENPSSQYW KEVAEKRRKA LYEALKENEK LHKEIEQKDN EIARLKKENK ELAEVAEHVQ YMAELIERLN GEPLDNFESL DNQEFDSEEE TVEDSLVEDS EIGTCAEGTV SSSTDAKPCI
Target Information
GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Geminin; Geminin GMNN; OTTHUMP00000039393; RP3 369A17.3; similar to Xenopus laevis geminin; unnamed protein product
Gene Aliases: Gem; GMNN; MGORS6
UniProt ID: (Human) O75496
Entrez Gene ID: (Human) 51053
regulation of DNA replication
regulation of mitotic cell cycle
negative regulation of DNA replication
organ morphogenesis
regulation of DNA-dependent DNA replication initiation
positive regulation of chromatin binding
negative regulation of cell cycle
negative regulation of transcription, DNA-templated
protein-containing complex assembly
DNA replication preinitiation complex assembly
negative regulation of DNA-dependent DNA replication
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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