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Invitrogen
CD90 Monoclonal Antibody (5E10), APC
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Product Details
A15726
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Horse,
Human,
Non-human primate,
Pig
Published species
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
5E10
Immunogen
HEL erythroleukemia cells
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.
Target Information
CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD90; CDw90; FLJ33325; membrane glycoprotein; Thy-1 antigen; Thy-1 membrane glycoprotein; Thy-1 T-cell antigen; unnamed protein product
Gene Aliases: CD90; CDw90; thy-1; THY1
UniProt ID: (Human) P04216
Entrez Gene ID: (Horse) 100063377, (Pig) 100271931, (Human) 7070
angiogenesis
regulation of cell-matrix adhesion
regulation of immune system process
positive regulation of cellular extravasation
negative regulation of protein kinase activity
cytoskeleton organization
cell adhesion
cell surface receptor signaling pathway
integrin-mediated signaling pathway
cell-cell signaling
regulation of cell migration
negative regulation of cell migration
heterotypic cell-cell adhesion
receptor clustering
positive regulation of GTPase activity
positive regulation of cell adhesion
retinal cone cell development
focal adhesion assembly
negative regulation of axonogenesis
T cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of focal adhesion assembly
negative regulation of neuron projection regeneration
cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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